中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共80条,第1-10条 帮助

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GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1 期刊论文  OAI收割
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11
作者:  
Zhou, Dongsheng;  Lv, Dan;  Wang, Zhen;  Zhang, Yanhua;  Chen, Zhongming
  |  收藏  |  浏览/下载:91/0  |  提交时间:2019/01/08
Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 118, 页码: 27-33
作者:  
Liu, Peihong;  Du, Yongli;  Song, Lianhua;  Shen, Jingkang;  Li, Qunyi
  |  收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
A sensitive and efficient method for determination of N-acetylhexosamines and N-acetylneuraminic acid in breast milk and milk-based products by high-performance liquid chromatography via UV detection and mass spectrometry identification 期刊论文  OAI收割
journal of chromatography b-analytical technologies in the biomedical and life sciences, 2016, 卷号: 1011, 页码: 14-23
作者:  
Wu, Chuanxiang;  Xia, Lian;  Liu, Lijie;  Qu, Fengli;  Sun, Zhiwei
收藏  |  浏览/下载:24/0  |  提交时间:2016/12/19
Two new phenol derivatives from Stereum hirsutum FP-91666 期刊论文  OAI收割
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2015, 卷号: 17, 期号: 4, 页码: 324-328
作者:  
Duan, Yuan-Chang;  Meng, Xin-Xin;  Yang, Yan-Long;  Yang, Yin-He;  Zhao, Pei-Ji
收藏  |  浏览/下载:19/0  |  提交时间:2015/06/29
Highly Syndioselective 3,4-Trans Polymerization of (E)-1-(4-Methylpheny1)-1,3-butadiene by Fluorenyl N-Heterocyclic Carbene Ligated Lutetium Bis(alkyl) Precursor 期刊论文  OAI收割
macromolecules, 2015, 卷号: 48, 期号: 7, 页码: 1999-2005
作者:  
Yao,Changguang;  Lin,Fei;  Wang,Meiyan;  Liu,Dongtao;  Liu,Bo
收藏  |  浏览/下载:25/0  |  提交时间:2016/05/06
Synthesis and Characterization of Soft-Hard Stereoblock Polybutadiene with Fe(2-EHA)3/Al(i-Bu)3/DEP Catalyst System 期刊论文  OAI收割
journal of polymer science part a-polymer chemistry, 2015, 卷号: 53, 期号: 10, 页码: 1182-1188
作者:  
Zheng, Wenjie;  Wang, Feng;  Bi, Jifu;  Zhang,Chunyu;  Hu,Yanming
收藏  |  浏览/下载:24/0  |  提交时间:2016/05/20
Half-titanocene 5-t-butyl-2-(1-(arylimino)methyl)quinolin-8-olate chlorides: Synthesis, characterization and ethylene (co-) polymerization behavior 期刊论文  OAI收割
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2014, 卷号: 753, 页码: 34-41
作者:  
Yan, Qing;  Yang, Wenhong;  Chen, Langqiu;  Wang, Lin;  Redshaw, Carl
  |  收藏  |  浏览/下载:24/0  |  提交时间:2019/04/09
Antioxidants in volatile Mail lard reaction products: Identification and interaction 期刊论文  OAI收割
lwt-food science and technology, 2013, 卷号: 53, 期号: 1, 页码: 22-28
作者:  
Yu, Xiangying;  Zhao, Mingyue;  Liu, Fei;  Zeng, Shitong;  Hu, Jun
收藏  |  浏览/下载:35/0  |  提交时间:2015/11/09
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  
Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载:44/0  |  提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
Catalyst-free one-pot synthesis of isoindolin-1-imine derivatives via three-component reaction 期刊论文  OAI收割
ARKIVOC, 2013, 页码: 413-423
作者:  
Shen, Sida;  Pham Van Khang;  Chen, Yijia;  Lei, Min;  Hu, Lihong
  |  收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08