中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
长春应用化学研究所 [18]
上海药物研究所 [13]
化学研究所 [8]
西北高原生物研究所 [7]
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期刊论文 [78]
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GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1
期刊论文
OAI收割
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11
作者:
Zhou, Dongsheng
;
Lv, Dan
;
Wang, Zhen
;
Zhang, Yanhua
;
Chen, Zhongming
  |  
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2019/01/08
GLYX-13
disrupted-in-schizophrenia 1
N-methyl-D-aspartate receptor
N-methyl D-aspartate receptor subtype 2B
schizophrenia
Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 118, 页码: 27-33
作者:
Liu, Peihong
;
Du, Yongli
;
Song, Lianhua
;
Shen, Jingkang
;
Li, Qunyi
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Type 2 diabetes mellitus
Methyl salicylate derivatives
ABC type PTP1B inhibitor
A sensitive and efficient method for determination of N-acetylhexosamines and N-acetylneuraminic acid in breast milk and milk-based products by high-performance liquid chromatography via UV detection and mass spectrometry identification
期刊论文
OAI收割
journal of chromatography b-analytical technologies in the biomedical and life sciences, 2016, 卷号: 1011, 页码: 14-23
作者:
Wu, Chuanxiang
;
Xia, Lian
;
Liu, Lijie
;
Qu, Fengli
;
Sun, Zhiwei
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2016/12/19
N-acetylhexosamines
N-acetylneuraminic acid
Pre-column derivatization
1-(2-naphthyl)-3-methyl-5-pyrazolone
HPLC-UV-MS/MS
Milk-based products
Two new phenol derivatives from Stereum hirsutum FP-91666
期刊论文
OAI收割
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2015, 卷号: 17, 期号: 4, 页码: 324-328
作者:
Duan, Yuan-Chang
;
Meng, Xin-Xin
;
Yang, Yan-Long
;
Yang, Yin-He
;
Zhao, Pei-Ji
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2015/06/29
5-hydroxy-4-(hydroxymethyl)-2-(3-methylbut-2-en-1-yl)cyclohex-4-en-1-one
2-(3-methyl-2-buten-1-yl)-4-methoxyethyl-phenol
Stereum hirsutum FP-91666
Stereaceae
Highly Syndioselective 3,4-Trans Polymerization of (E)-1-(4-Methylpheny1)-1,3-butadiene by Fluorenyl N-Heterocyclic Carbene Ligated Lutetium Bis(alkyl) Precursor
期刊论文
OAI收割
macromolecules, 2015, 卷号: 48, 期号: 7, 页码: 1999-2005
作者:
Yao,Changguang
;
Lin,Fei
;
Wang,Meiyan
;
Liu,Dongtao
;
Liu,Bo
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2016/05/06
3
METAL COMPLEXES BEARING
ZIEGLER-NATTA CATALYSTS
ISOPRENE POLYMERIZATION
1
SYNDIOTACTIC 1
STEREOSPECIFIC CATALYST
CATIONIC POLYMERIZATION
STRUCTURAL CHEMISTRY
METHYL METHACRYLATE
4-SELECTIVE LIVING POLYMERIZATION
3-DIENE POLYMERIZATION
2-POLYBUTADIENE
Synthesis and Characterization of Soft-Hard Stereoblock Polybutadiene with Fe(2-EHA)3/Al(i-Bu)3/DEP Catalyst System
期刊论文
OAI收割
journal of polymer science part a-polymer chemistry, 2015, 卷号: 53, 期号: 10, 页码: 1182-1188
作者:
Zheng, Wenjie
;
Wang, Feng
;
Bi, Jifu
;
Zhang,Chunyu
;
Hu,Yanming
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2016/05/20
CONTROLLED/LIVING RADICAL POLYMERIZATION
CHAIN TRANSFER POLYMERIZATION
BLOCK-COPOLYMERS
SYNDIOTACTIC 1
LIVING POLYMERIZATION
STEREOSPECIFIC POLYMERIZATION
POLY(METHYL METHACRYLATE)
ELASTOMERIC POLYPROPYLENE
TRIBLOCK COPOLYMERS
C-13 NMR
2-POLYBUTADIENE
Half-titanocene 5-t-butyl-2-(1-(arylimino)methyl)quinolin-8-olate chlorides: Synthesis, characterization and ethylene (co-) polymerization behavior
期刊论文
OAI收割
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2014, 卷号: 753, 页码: 34-41
作者:
Yan, Qing
;
Yang, Wenhong
;
Chen, Langqiu
;
Wang, Lin
;
Redshaw, Carl
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/04/09
5-t-butyl-2-(1-(Arylimino)Methyl)Quinolin-8-ol
Half-titanocene
Ethylene Polymerization
Co-polymerization
Antioxidants in volatile Mail lard reaction products: Identification and interaction
期刊论文
OAI收割
lwt-food science and technology, 2013, 卷号: 53, 期号: 1, 页码: 22-28
作者:
Yu, Xiangying
;
Zhao, Mingyue
;
Liu, Fei
;
Zeng, Shitong
;
Hu, Jun
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2015/11/09
Antioxidant
Volatile Maillard reaction products (MRPs)
2
2
2-Hydroxy-3-methyl-2-cyclopenten-1-one (CP)
5-Dimethyl-4-hydroxy-3(2H)furanone (DMHF)
3-Dihydro-3
5-dihydroxy-6-methyl-4H-pyran-4-one (DDMP)
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells
期刊论文
OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:
Zeng, Guang-Zhi
;
Fan, Jun-Ting
;
Xu, Jun-Ju
;
Li, Yan
;
Tan, Ning-Hua
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)
one of the major components isolated from the traditional
Chinese medicine Rubia yunnanensis
exhibited inhibitory activity on the proliferation of several
human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay
and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle
arrest in human cervical carcinoma HeLa cells. Further
MTA was found to induce apoptosis of HeLa cells
through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and
release of cytochrome c into the cytosol
which caused the cleavage of caspase and poly(ADP-ribose)
polymerase and finally triggered the apoptosis. Furthermore
the p53/p21/Cdc2-cyclin B1 signaling was
found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of
cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused
the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of
R. yunnanensis
a folk anti-cancer herb used in Yunnan
China.
Catalyst-free one-pot synthesis of isoindolin-1-imine derivatives via three-component reaction
期刊论文
OAI收割
ARKIVOC, 2013, 页码: 413-423
作者:
Shen, Sida
;
Pham Van Khang
;
Chen, Yijia
;
Lei, Min
;
Hu, Lihong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
2-cyanobenzaldehyde
3-methyl-1H-pyrazol-5(4H)-one
1,3-dimethyl-1H-pyrazol-5(4H)-one
isoindolin-1-imine
multi-component reaction