中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
中国科学院大学 [1]
采集方式
OAI收割 [9]
iSwitch采集 [1]
内容类型
期刊论文 [10]
发表日期
2019 [2]
2018 [1]
2017 [3]
2016 [4]
学科主题
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Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268
作者:
Liu, Xia
;
Wang, Wei
;
Chen, Hua-li
;
Zhang, Hai-yan
;
Zhang, Nai-xia
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Alzheimer's disease
type 2 diabetes
APP/PS1 transgenic mice
metabolomics
NMR
glucose metabolism dysfunctions
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
期刊论文
OAI收割
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:
Guo, Xiaodan
;
Lv, Jianlu
;
Lu, Jian
;
Fan, Lei
;
Huang, Xi
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Ginseng
Autophagy
BACE1
ER stress
Amyloid beta
Apoptosis
APP/PS1 transgenic mice
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both A beta and Tau pathologies
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 1, 页码: 9-28
作者:
Li, Cong
;
Gu, Xiao-dan
;
Lei, Min
;
Wu, Jia-yi
;
Jin, Jia-zhen
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-beta
Tau
autophagy
BACE1
GSK3 beta
PI3K
thamnoliavermicularisextractimproveslearningabilityinappps1transgenicmicebyamelioratingbothaandtaupathologies
期刊论文
OAI收割
actapharmacologicasinica, 2017, 卷号: 38, 期号: 1, 页码: 9
作者:
Li Cong
;
Guo Xiaodan
;
Lei Min
;
Wu Jiayi
;
Jin Jiazhen
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-β
Tau
autophagy
BACE1
GSK3β
PI_3K
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Aβ and Tau pathologies
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 1, 页码: 9
作者:
Li Cong
;
Guo Xiaodan
;
Lei Min
;
Wu Jiayi
;
Jin Jiazhen
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/12/24
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-β
Tau
autophagy
BACE1
GSK3β
PI_3K
Small molecule lx2343 ameliorates cognitive deficits in ad model mice by targeting both amyloid beta production and clearance
期刊论文
iSwitch采集
Acta pharmacologica sinica, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Xu, Xin
;
Zhu, Zhi-yuan
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/05/09
Alzheimer's disease
N-(1,3-benzodioxol-5-yl)-2-[5-chloro-2-methoxy(phenylsulfonyl)anilino]acetamide (lx2343)
Streptozotocin
Amyloid beta
Pi3k
Autophagy
App/ps1 transgenic mice
Cognitive deficit
Bace1
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Xu, Xin
;
Zhu, Zhi-yuan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Alzheimer's disease
N-(1,3-benzodioxol-5-yl)-2-[5-chloro-2-methoxy(phenylsulfonyl)anilino]acetamide (LX2343)
streptozotocin
amyloid beta
BACE1
PI3K
autophagy
APP/PS1 transgenic mice
cognitive deficit
smallmoleculelx2343amelioratescognitivedeficitsinadmodelmicebytargetingbothamyloidproductionandclearance
期刊论文
OAI收割
actapharmacologicasinica, 2016, 卷号: 000, 期号: 010, 页码: 1281
作者:
Guo Xiaodan
;
Sun Guanglong
;
Zhou Tingting
;
Xu Xin
;
Zhu Zhiyuan
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Alzheimer's disease
N-(1
3-benzodioxol-5-yl)-2-5-chloro-2-methoxy(phenylsulfonyl)anilinoacetamide (LX2343)
streptozotocin
amyloid β
BACE1
PI3K
autophagy
APP/PS1 transgenic mice
cognitive deficit
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance
期刊论文
OAI收割
中国药理学报:英文版, 2016, 卷号: 000, 期号: 010, 页码: 1281
作者:
Guo Xiaodan
;
Sun Guanglong
;
Zhou Tingting
;
Xu Xin
;
Zhu Zhiyuan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
Alzheimer's disease
N-(1
3-benzodioxol-5-yl)-2-5-chloro-2-methoxy(phenylsulfonyl)anilinoacetamide (LX2343)
streptozotocin
amyloid β
BACE1
PI3K
autophagy
APP/PS1 transgenic mice
cognitive deficit