中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [19]
上海生物化学与细胞生... [8]
海洋研究所 [4]
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期刊论文 [59]
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浏览/检索结果:
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Pharmacological targeting of Axin2 suppresses cell growth and metastasis in colorectal cancer
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2023, 页码: 21
作者:
Cheng, Li-Zhi
;
Huang, Dan-Ling
;
Tang, Zhang-Rui
;
Zhang, Jia-Hao
;
Xiong, Ting
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
colorectal cancer progression
GSK3 beta-Axin2 interaction
small-molecule inhibitor
Snail
beta-Trcp2
Hypoglycemic effect of Nitraria tangutorum fruit by inhibiting glycosidase and regulating IRS1/PI3K/AKT signalling pathway and its active ingredient identification by UPLC-MS
期刊论文
OAI收割
FOOD & FUNCTION, 2023, 卷号: 14, 期号: 17, 页码: 7869
作者:
Jiang, Sirong
;
Wang, Luya
;
Jia, Wenjing
;
Wu, Di
;
Wu, Li
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/01
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14
作者:
Huang, Su-Ling
;
Xie, Wei
;
Ye, Yang-Liang
;
Liu, Jia
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/11/11
type 2 diabetes mellitus
coronarin A
glycogen synthesis
gluconeogenesis
mTORC1
IRS1
Nrf2-mediated liver protection by 18 beta-glycyrrhetinic acid against pyrrolizidine alkaloid-induced toxicity through PI3K/Akt/GSK3 beta pathway
期刊论文
OAI收割
PHYTOMEDICINE, 2022, 卷号: 102, 页码: 12
作者:
Wang, Zhangting
;
Ma, Jiang
;
He, Yisheng
;
Miu, Kai-Kei
;
Yao, Sheng
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/08/30
Pyrrolizidine alkaloids
Herb-induced liver injury
18 beta-glycyrrhetinic acid
Liquorice
Nuclear factor erythroid-2-related factor 2
PI3K/Akt/GSK3 beta
GSK3 beta palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axis
期刊论文
OAI收割
ONCOGENESIS, 2022, 卷号: 11
作者:
Zhao, Chenggang
;
Yu, Huihan
;
Fan, Xiaoqing
;
Niu, Wanxiang
;
Fan, Junqi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/23
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
OAI收割
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:
Zhang, Ning
;
Tian, Yu-Nan
;
Zhou, Li-Na
;
Li, Meng-Zhu
;
Chen, Hua-Dong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Development of Bisindole-Substituted Aminopyrazoles as Novel GSK-3 beta Inhibitors with Suppressive Effects against Microglial Inflammation and Oxidative Neurotoxicity
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 20, 页码: 3398-3408
作者:
Liu, Jian-Guo
;
Zhao, Danfeng
;
Gong, Qi
;
Bao, Fengxia
;
Chen, Wen-Wen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2021/05/24
Glycogen synthase kinase-3
bisindole-substituted aminopyrazoles
Alzheimer's disease
oxidative neurotoxicity
microglial inflammation
Gandou decoction, a Chinese medicinal formula, in the treatment of hepatic injury by Wnt/beta-catenin pathway regulation in models of Wilson disease
期刊论文
OAI收割
ANNALS OF PALLIATIVE MEDICINE, 2020, 卷号: 9
作者:
Gao, Manli
;
Geng, Hao
;
Wu, Peng
;
Dong, Jianjian
;
Li, Hai
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/11/30
Wilson disease (WD)
liver injury
Gandou decoction (GDD)
Wnt/beta-catenin pathway
oxidative stress
Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 3, 页码: 434-446
作者:
Feng, Hongxuan
;
Hu, Linghao
;
Zhu, Hongwen
;
Tao, Lingxue
;
Wu, Lei
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Blood-brain barrier
Brain ischemia
Cell cycle
Inflammation
Neuroprotection
Typical halogenated flame retardants affect human neural stem cell gene expression during proliferation and differentiation via glycogen synthase kinase 3 beta and T3 signaling
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 183, 页码: -
作者:
Liang, Shaojun
;
Liang, Shengxian
;
Zhou, Hui
;
Yin, Nuoya
;
Faiola, Francesco
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/09/10
Human neural stem cells (hNSCs)
TBBPA/TBBPS/TCBPA
BDE-209/BDE-47
Human neural developmental toxicity
GSK3 beta
T3 signaling