中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2025 [2]
2024 [1]
2022 [3]
2021 [1]
2020 [1]
学科主题
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The combination of BET and METTL3 inhibitors elicits synergistic antitumor effects in ovarian cancer cells
via
reducing SP1 and BCL-2 expression
期刊论文
OAI收割
LIFE SCIENCES, 2025, 卷号: 368, 页码: 14
作者:
Ou, Ying-Jie
;
Liu, Ben-Jin
;
Xuan, Yi-Fei
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
BET inhibitor
METTL3 inhibitor
Combination therapy
SP1
BCL-2
A patent review of BRD4 inhibitors (2020-present)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2025, 页码: 16
作者:
Chen, Yanfang
;
Zhou, Huanmin
;
Yu, Jiamin
;
Gao, Jing
;
Xue, Shengyu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
BET
BRD4
inhibitor
cancer treatment
selectivity
Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2024, 卷号: 223, 页码: 17
作者:
Zhang, Qian
;
Wu, Qian
;
Huan, Xia-Juan
;
Song, Shan -Shan
;
Bao, Xu-Bin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/06/27
BET inhibitor
NAE inhibitor
BIM
Apoptosis
Combination therapy
Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13
作者:
Luo, Menglan
;
Wu, Qian
;
Yang, Yueyue
;
Sun, Lin
;
Huan, Xiajuan
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/08/30
BET inhibitor
BRD4
Bivalent inhibitor
Anticancer
Selective bromodomain and extra-terminal bromodomain inhibitor inactivates macrophages and hepatic stellate cells to inhibit liver inflammation and fibrosis
期刊论文
OAI收割
BIOENGINEERED, 2022, 卷号: 13, 期号: 4, 页码: 10914-10930
作者:
Fu, Rong
;
Zu, Shi-Jia
;
Liu, Yan-Jun
;
Li, Jia-Cheng
;
Dang, Wen-Zhen
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/06/15
BET inhibitor
macrophage
hepatic stellate cell
inflammation
fibrosis
TNKS inhibitors potentiate proliferative inhibition of BET inhibitors via reducing beta-Catenin in colorectal cancer cells
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 卷号: 12, 期号: 3, 页码: 1069-+
作者:
Wu, Qian
;
Xuan, Yi-Fei
;
Su, Ai-Ling
;
Bao, Xu-Bin
;
Miao, Ze-Hong
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/06/15
BET inhibitor
Tankyrases inhibitor
beta-Catenin
antitumor activity
combination therapy
Multi-omics characterization of WNT pathway reactivation to ameliorate BET inhibitor resistance in liver cancer cells
期刊论文
OAI收割
GENOMICS, 2021, 卷号: 113, 期号: 3, 页码: 1057-1069
作者:
Liu, Yuwei
;
Xue, Mengzhu
;
Cao, Danyan
;
Qin, Lihuai
;
Wang, Ying
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/08/17
Multi-omics
BET inhibitor responses
WNT pathway
Liver cancer
Precise therapy
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
期刊论文
OAI收割
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:
Damaneh, Mohammadali Soleimani
;
Hu, Jian-Ping
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/07/01
BET inhibitor
Cell proliferation
Apoptosis
Anti-cancer agent