中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
合肥物质科学研究院 [1]
采集方式
OAI收割 [6]
内容类型
期刊论文 [6]
发表日期
2021 [1]
2020 [1]
2019 [3]
2018 [1]
学科主题
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Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936
作者:
Gao, Jing
;
Zhang, Hanwu
;
Zhou, Fengqi
;
Hou, Bo
;
Chen, Meiwan
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/08/17
Cancer immunotherapy
siRNA delivery
Acid-activatible micelleplex
CDK4
6 inhibitor
PD-L1 knockdown
Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma
期刊论文
OAI收割
JOURNAL OF CANCER, 2020, 卷号: 11
作者:
Zhu, Guanxia
;
Li, Xia
;
Li, Jiong
;
Zhou, Wei
;
Chen, Zhongjian
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/11/30
esophageal squamous cell carcinoma
oral squamous cell carcinoma
arsenic trioxide
cyclin D1
PD-L1
CDK4/6
Simultaneous inhibition of PI3K alpha and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-+
作者:
Wang, Yuxiang
;
Li, Xian
;
Liu, Xueling
;
Chen, Yi
;
Yang, Chunhao
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
PI3K alpha
CDK4/6
KRAS
NSCLC
CYH33
Simultaneous inhibition of PI3Kα and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-83
作者:
Wang, Yuxiang
;
Li, Xian
;
Liu, Xueling
;
Chen, Yi
;
Yang, Chunhao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/21
PI3K alpha
CDK4/6
KRAS
NSCLC
CYH33
Simultaneous inhibition of PI3Kα and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer
期刊论文
OAI收割
Cancer Biology and Medicine, 2019, 卷号: 16, 期号: 1, 页码: 66
作者:
Wang Yuxiang
;
Li Xian
;
Liu Xueling
;
Chen Yi
;
Yang Chunhao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/24
PI3Kα
CDK4/6
KRAS
NSCLC
CYH33
Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 140-153
作者:
Zha, Chuantao
;
Deng, Wenjia
;
Fu, Yan
;
Tang, Shuai
;
Lan, Xiaojing
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/01/08
Structure-based drug design
Selective CDK4/6 inhibitors
Structure-activity relationship study
In vivo antitumor activity