中国科学院机构知识库网格系统: 检索

浏览/检索结果: 共5条，第1-5条

帮助

条数/页：排序方式：
	E3 ligase ligand optimization of Clinical PROTACs 期刊论文 OAI收割 FRONTIERS IN CHEMISTRY, 2023, 卷号: 11, 页码: 15 作者: Jiang, Hanrui; Xiong, Huan; Gu, Shuang-Xi; Wang, Mingliang \| 收藏 \| 浏览/下载：22/0 \| 提交时间：2023/04/10 PROTACs E3 ubiquitin ligase ligand structure optimization clinical trials CRBN
	Design, synthesis, and biological evaluation of Wee1 kinase degraders 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243, 页码: 21 作者: Zhu, Shulei; Liu, Jieyu; Xiao, Donghuai; Wang, Peipei; Ma, Jingkun \| 收藏 \| 浏览/下载：61/0 \| 提交时间：2022/11/11 CRBN Wee1 PROTAC Degradation
	Design, Synthesis, and Biological Evaluation of HDAC Degraders with CRBN E3 Ligase Ligands 期刊论文 OAI收割 MOLECULES, 2021, 卷号: 26, 期号: 23, 页码: 19 作者: Lu, Yingxin; Sun, Danwen; Xiao, Donghuai; Shao, Yingying; Su, Mingbo \| 收藏 \| 浏览/下载：48/0 \| 提交时间：2022/06/15 HDAC degraders CRBN ligands proteins of interest benzyl alcohol linkage
	Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14 作者: Yang, Xiangbo; Wang, Zhijia; Pei, Yuan; Song, Ning; Xu, Lei \| 收藏 \| 浏览/下载：40/0 \| 提交时间：2021/08/17 SHP2 degradation Proteolysis targeting chimera (PROTAC) Thalidomide-based heterobifunctional molecules E3 ubiquitin ligase CRBN
	The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者: Hao, Bing-bing; Li, Xiao-jing; Jia, Xing-long; Wang, Yu-xing; Zhai, Lin-hui \| 收藏 \| 浏览/下载：31/0 \| 提交时间：2020/07/01 immunomodulatory drugs (IMiDs) CC-885 BNIP3L mitophagy CRBN acute myeloid leukemia mitochondria-targeting drugs