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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
昆明植物研究所 [2]
化学研究所 [1]
西北高原生物研究所 [1]
心理研究所 [1]
自动化研究所 [1]
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OAI收割 [10]
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期刊论文 [10]
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2025 [1]
2024 [1]
2021 [2]
2015 [1]
2014 [1]
2013 [1]
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Biochemist... [1]
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Therapeutic potential and pharmacological mechanisms of Traditional Chinese Medicine in gout treatment
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 21
作者:
Guo, Jing-wen
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
gout
hyperuricemia
gouty arthritis
Traditional Chinese Medicine
TCM formula
Chinese herb
Dual-channel hypergraph convolutional network for predicting herb-disease associations
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 25, 期号: 2, 页码: 13
作者:
Hu, Lun
;
Zhang, Menglong
;
Hu, Pengwei
;
Zhang, Jun
;
Niu, Chao
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/08/22
herb-disease association prediction
network pharmacology
hypergraph convolutional network
multi-target multi-component
Chinese traditional medicine
Astragalus membranaceus root supplementation improves average daily gain, rumen fermentation, serum immunity and antioxidant indices of Tibetan sheep
期刊论文
OAI收割
ANIMAL, 2021, 卷号: 15, 期号: 1
作者:
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/11/18
Botanical feed additives
Chinese traditional herb
Healthy feeding
Qinghai-Tibetan Plateau
Secondary compounds
Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen)
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:
Gao,Zhen
;
Huang,Xiao-Yan
;
Geng,Chang-An
;
Li,Tian-Ze
;
Chen,Ji-Jun
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/04/02
Artemisia capillaris
Coumaric acid analogues
Antihepatic fibrosis effects
HSC-LX2
Extracellular matrix
TRADITIONAL CHINESE HERB
ACTIVE CONSTITUENTS
LIVER FIBROSIS
Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis
期刊论文
OAI收割
ONCOTARGET, 2015, 卷号: 6, 期号: 35, 页码: 38283-38295
作者:
Wu, Min
;
Lu, Peng
;
Shi, Luwen
;
Li, Shao
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2016/03/19
traditional Chinese medicine
cancer treatment
medical insurance
nationwide survey
herb-drug network
Traditional Chinese herbs as chemical resource library for drug discovery of anti-infective and anti-inflammatory
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2014, 卷号: 155, 期号: 1, 页码: 589-598
作者:
Ding, Weixian
;
Gu, Jiangyong
;
Cao, Liang
;
Li, Na
;
Ding, Gang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/04/09
Traditional Chinese Herb
Anti-infection
Anti-inflammatory
Chemical Informatics
Network Pharmacology
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells
期刊论文
OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:
Zeng, Guang-Zhi
;
Fan, Jun-Ting
;
Xu, Jun-Ju
;
Li, Yan
;
Tan, Ning-Hua
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)
one of the major components isolated from the traditional
Chinese medicine Rubia yunnanensis
exhibited inhibitory activity on the proliferation of several
human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay
and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle
arrest in human cervical carcinoma HeLa cells. Further
MTA was found to induce apoptosis of HeLa cells
through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and
release of cytochrome c into the cytosol
which caused the cleavage of caspase and poly(ADP-ribose)
polymerase and finally triggered the apoptosis. Furthermore
the p53/p21/Cdc2-cyclin B1 signaling was
found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of
cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused
the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of
R. yunnanensis
a folk anti-cancer herb used in Yunnan
China.
Antibacterial and Anti-inflammatory Activity of Traditional Chinese Herb Pairs, Angelica sinensis and Sophora flavescens
期刊论文
OAI收割
INFLAMMATION, 2012, 卷号: 35, 期号: 3, 页码: 913-919
作者:
Han, Chunchao
;
Guo, Jianyou
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2015/10/08
traditional Chinese herb pairs
inflammation
Angelica sinensis
S. flavescens
LPS
Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2006, 卷号: 1760, 期号: 10, 页码: 1505-1512
作者:
Zhang, Wei
;
Hong, Di
;
Zhou, Yueyang
;
Zhang, Yinan
;
Shen, Qiang
  |  
收藏
  |  
浏览/下载:142/0
  |  
提交时间:2019/01/08
PTP1B
inhibitor
ursolic acid
traditional Chinese medicinal herb
derivative
competitive
insulin receptor
glucose uptake