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Chinese Academy of Sciences Institutional Repositories Grid
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De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 13
作者:
Xu, Yali
;
Zhao, Wensi
;
Nie, Hui-Jun
;
Wang, Jiamin
;
Fu, Jingjing
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/05/27
Chemoproteomics
Genetic code expansion
Molecular glue degrader
Photo-crosslinking
Targeted protein degradation
Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:
Zeng, Yanping
;
Xiao, Jian
;
Shi, Li
;
Li, Yangsha
;
Xu, Yuanxin
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2025/04/01
LC3B
CDK9
Degradation
Protein complex
Excavation disturbance response of deep-buried tunnel with novel dynamic anisotropic mechanical model and failure degree index
期刊论文
OAI收割
TUNNELLING AND UNDERGROUND SPACE TECHNOLOGY, 2025, 卷号: 158, 页码: 18
作者:
Zheng, Zhi
;
Li, Ronghua
;
Pan, Pengzhi
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/27
True triaxial disturbance test
Mechanical parameter degradation
Anisotropic mechanical model
Disturbance fracture degree index
Excavation response analysis
Silver loaded APTES-boron nitride with enhanced visible light photocatalytic properties for sewage degradation
期刊论文
OAI收割
MATERIALS TODAY CHEMISTRY, 2025, 卷号: 45, 页码: 9
作者:
Zhou, Anjie
;
Zhang, Ruiyong
;
Geng, Yongjuan
;
Li, Shaochun
;
Ban, Xinze
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/07/11
Aminopropyltriethoxysilane
Boron nitride
Photocatalytic degradation
Photocatalytic sterilization
Noble metal modified photocatalytic materials
Functional shift in soil microbiome with decline in photosynthetic carbon input signifies rapid decrease of soil organic carbon during alpine grassland degradation
期刊论文
OAI收割
BIOLOGY AND FERTILITY OF SOILS, 2025, 卷号: N/A
作者:
Song, Minghua
;
Pang, Rui
;
Tian, Yuqiang
;
Li, Yikang
;
Wang, Guiqiang
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/04/21
C-13 tracer
Photosynthetic carbon incorporation
Phospholipid fatty acid profiles
Stable isotope
Grassland degradation
Tibetan Plateau
Effect of polystyrene micro/nanoplastics on PCBs removal in constructed wetlands planted with
Myriophyllum aquaticum
期刊论文
OAI收割
ENVIRONMENTAL RESEARCH, 2025, 卷号: 269, 页码: 9
作者:
Wang, Shuang
;
Liu, Jun
;
Kang, Rongjie
;
Liu, Ya
;
Zhao, Xuan
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收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/03
Polychlorinated biphenyls
Plastic
Different size
Myriophyllum aquaticum
Plant uptake
Microbial degradation
PCB-Degrading enzymes
Self-Oxygenating PROTAC Microneedle for Spatiotemporally-Confined Protein Degradation and Enhanced Glioblastoma Therapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2025, 页码: 13
作者:
Jiang, Xingyu
;
Lai, Yi
;
Xia, Wenzheng
;
Yang, Wenfang
;
Wang, Junjue
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
acid-activatable photodynamic therapy
double-layered microneedle
glioblastoma therapy
light-activatable PROTAC prodrug
protein degradation
Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17
作者:
Hu, Linghao
;
Xu, Hesong
;
Xu, Ye
;
Chen, Haowen
;
Jiang, Hanrui
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/04/01
NSD2
RE-IIBP
Targeted protein degradation
Multiple myeloma
Review of Permafrost Degradation in the Mongolian Plateau
期刊论文
OAI收割
LAND, 2025, 卷号: 14, 期号: 2, 页码: 383
作者:
Li, Fengjiao
;
Wang, Juanle
;
Li, Pengfei
;
Dashtseren, Avirmed
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/21
permafrost degradation
Mongolian Plateau
permafrost monitoring
remote sensing
ecological environment