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浏览/检索结果: 共4条，第1-4条 帮助

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Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:  Geng, Kaijun;  Liu, Hongchun;  Song, Zilan;  Zhang, Chi;  Zhang, Minmin
  |  收藏  |  浏览/下载：190/0  |  提交时间：2019/01/08
Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61
作者:  Li, Xin;  Yang, Changyong;  Wan, Hong;  Zhang, Ge;  Feng, Jun
  |  收藏  |  浏览/下载：149/0  |  提交时间：2019/01/08
Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 期号: 无, 页码: 674-697
作者:  Chen, Yongfei;  Wu, Jiaxin;  Wang, Aoli;  Qi, Ziping;  Jiang, Taoshan
  |  收藏  |  浏览/下载：916/0  |  提交时间：2018/08/17
discoveryandcharacterizationofanovelinhibitorofcdc25blgh00045 期刊论文  OAI收割
actapharmacologicasinica, 2008, 卷号: 29, 期号: 10, 页码: 1268
作者:  Xu FENG;  Lina WANG;  Yueyang ZHOU;  Haiping YU;  Qiang SHEN
  |  收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01