中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [14]
合肥物质科学研究院 [7]
金属研究所 [5]
化学研究所 [1]
昆明植物研究所 [1]
过程工程研究所 [1]
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OAI收割 [30]
iSwitch采集 [1]
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期刊论文 [31]
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2024 [1]
2021 [3]
2020 [2]
2018 [2]
2017 [8]
2016 [1]
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Integrative study of lung cancer adeno-to-squamous transition in EGFR TKI resistance identifies RAPGEF3 as a therapeutic target
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 12, 页码: 20
作者:
Wang, Hua
;
Tang, Shijie
;
Wu, Qibiao
;
He, Yayi
;
Zhu, Weikang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/02/28
EGFR-mutant lung cancer
adeno-to-squamous transition
tyrosine kinase inhibitor resistance
transcription factor network
RAPGEF3
The genomic landscape of young and old lung cancer patients highlights age-dependent mutation frequencies and clinical actionability in young patients
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF CANCER, 2021
作者:
Cai, Lei
;
Chen, Yong
;
Tong, Xiaoling
;
Wu, Xue
;
Bao, Hua
  |  
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2021/06/15
EGFR
ERBB2
gene fusions
tyrosine kinase inhibitors
young lung cancer patients
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
OAI收割
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
Musarin, a novel protein with tyrosine kinase inhibitory activity from Trametes versicolor, accepted inhibits colorectal cancer stem cell growth
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 144, 页码: 112339
作者:
He,YingYing
;
Liu,Shubai
;
Newburg,David S.
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/04/02
Trametes versicolor
Cancer stem cell
Tyrosine kinase inhibitor
EGFR
Colorectal cancer
FACTOR RECEPTOR
POLYSACCHAROPEPTIDE
RESISTANCE
TARGET
EGFR
TOOL
PSP
DNA
Tumor Mutation Burden Correlates With Efficacy of Chemotherapy/Targeted Therapy in Advanced Non-Small Cell Lung Cancer
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Lin, Chen
;
Shi, Xun
;
Zhao, Jun
;
He, Qiong
;
Fan, Yun
  |  
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/10/26
tumor mutation burden (TMB)
clinical benefit
epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)
chemotherapy
non-small cell lung cancer (NSCLC)
BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFR(T790M) mutation
期刊论文
OAI收割
THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6122-6135
作者:
Yin, Weimin
;
Zhao, Yuge
;
Kang, Xuejia
;
Zhao, Pengfei
;
Zhao, Xuhong
  |  
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2020/07/01
brain targeting delivery
tumor-associated macrophage
non-small cell lung cancer (NSCLC)
drug resistance
tyrosine kinase inhibitors (TKI)
EGFR T790M mutation
Identifying egfr-expressed cells and detecting egfr multi-mutations at single-cell level by microfluidic chip
期刊论文
iSwitch采集
Nano-micro letters, 2018, 卷号: 10, 期号: 1, 页码: 10
作者:
Li, Ren
;
Zhou, Mingxing
;
Li, Jine
;
Wang, Zihua
;
Zhang, Weikai
收藏
  |  
浏览/下载:109/0
  |  
提交时间:2019/04/23
Egfr mutation
Single-cell analysis
Microfluidic chip
Tyrosine kinase inhibitor
Targeting HER2 Aberrations in Non-Small Cell Lung Cancer with Osimertinib
期刊论文
OAI收割
CLINICAL CANCER RESEARCH, 2018, 卷号: 24, 期号: 11, 页码: 2594-2604
作者:
Liu, Shengwu
;
Hai, Josephine
;
Wang, Xiaoen
;
Quinn, Max M.
;
Gao, Peng
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/04/28
Receptor Tyrosine Kinase
Phase-ii Trial
Bromodomain Inhibition
Combination Therapy
Acquired-resistance
Domain Mutations
Bet Bromodomains
Breast-cancer
Egfr
Mutant
Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61
作者:
Li, Xin
;
Yang, Changyong
;
Wan, Hong
;
Zhang, Ge
;
Feng, Jun
  |  
收藏
  |  
浏览/下载:150/0
  |  
提交时间:2019/01/08
Pyrotinib
HER2-postive breast cancer
Irreversible EGFR/HER2 dual tyrosine kinase
inhibitor
Preclinical
Clinical
Safety
Drug metabolism
Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2017, 卷号: 5
作者:
Hu, Xiuqin
;
Wang, Disha
;
Tong, Yi
;
Tong, Linjiang
;
Wang, Xia
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/01/08
EGFR
tyrosine kinase inhibitors
anilinopyrtmidine
glycosides
carbohydrate-based drugs