中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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合肥物质科学研究院 [89]
上海药物研究所 [64]
上海生物化学与细胞... [19]
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期刊论文 [256]
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浏览/检索结果:
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
;
Long, Li
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13
作者:
Zhou, Ji
;
Zhang, Xu-Chao
;
Xue, Shan
;
Dai, Mengdi
;
Wang, Yueliang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Pei, Jin-peng
;
Wang, Yue
;
Ma, Lan-ping
;
Wang, Xin
;
Liu, Liang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
AXL
NSCLC
TNBC
M2-macrophage
antibody-drug conjugate
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
A retrospective study on the efficacy and safety of Endostar with chemotherapy in EGFR-TKI-resistant NSCLC
期刊论文
OAI收割
BMC PULMONARY MEDICINE, 2023, 卷号: 23, 期号: 1
作者:
Bing Han
;
Yanrong Kang
;
Haiji Wang
;
Jian Wang
;
Rong Shen
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/01/26
Gefitinib enhances the anti-tumor immune response against EGFR-mutated NSCLC by upregulating B7H5 expression and activating T cells via CD28H
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ONCOLOGY, 2022, 卷号: 61
作者:
Guo, Huihui
;
Zhang, Xilin
;
Xie, Shangzhi
;
Chen, Tianwei
;
Xie, Dong
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2022/12/22
gefitinib
CD28H
NSCLC
EGFR mutation
Deep learning for predicting major pathological response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer: A multicentre study
期刊论文
OAI收割
EBIOMEDICINE, 2022, 卷号: 86, 页码: 13
作者:
She, Yunlang
;
He, Bingxi
;
Wang, Fang
;
Zhong, Yifan
;
Wang, Tingting
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/02/22
Deep learning
Neoadjuvant chemoimmunotherapy
Major pathological response
Non-small cell lung cancer
Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non-Small Cell Lung Cancer Cells
期刊论文
OAI收割
MOLECULAR CANCER RESEARCH, 2022, 卷号: 20, 期号: 12, 页码: 1785-1798
作者:
Sun, Lin
;
Wu, Qian
;
Huan, Xia-Juan
;
Tian, Chang-Qing
;
Wang, Ying-Qing
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/21