中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
兰州化学物理研究所 [2]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2022 [2]
2015 [1]
2012 [2]
学科主题
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GP-14 protects against severe hypoxia-induced neuronal injury through the AKT and ERK pathways and its induced transcriptome profiling alteration
期刊论文
OAI收割
Toxicology and Applied Pharmacology, 2022, 期号: 448, 页码: 116092
作者:
Ya-Nan Geng
;
Ming Zhao
;
Jun-Li Yang
;
Xiang Cheng
;
Ying Han
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/11/30
Gypenoside-14 (GP-14)
Neuronal Damage
Hypoxia
Transcriptome Sequencing
Neuroprotection
A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-κB signaling pathway in a mouse high-altitude cerebral edema (HACE) model
期刊论文
OAI收割
International Immunopharmacology, 2022, 期号: 107, 页码: 108675
作者:
Ya-Nan Geng
;
Jun-Li Yang
;
Xiang Cheng
;
Ying Han
;
Feng Yan
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/11/30
Gypenoside
Neuroinflammation
Blood brain barrier
High altitude cerebral edema
NF-κB signaling pathway
Simultaneous determination of gypenoside LVI, gypenoside XLVI, 2 alpha-OH-protopanaxadiol and their two metabolites in rat plasma by LC MS/MS and its application to pharmacokinetic studies
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2015, 卷号: 1005, 页码: 9-16
作者:
Zhang, Lihua
;
Lin, Yunfei
;
Guan, Huashi
;
Hu, Lihong
;
Pan, Guoyu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Gypenoside
2 alpha-OH-Protopanaxadiol
Gynostemma pentaphyllum
Validation
Pharmacokinetic
Reversal of P-gp and MRP1-mediated multidrug resistance by H6, a gypenoside aglycon from Gynostemma pentaphyllum, in vincristine-resistant human oral cancer (KB/VCR) cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2012, 卷号: 696, 期号: 1-3, 页码: 43-53
作者:
Zhu, Hengrui
;
Liu, Zulong
;
Tang, Lisha
;
Liu, Junhua
;
Zhou, Mei
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Gypenoside aglycon
Gynostemma pentaphyllum
Multidrug resistance (MDR)
KB/VCR cells
P-glycoprotein (P-gp)
Multidrug resistance associated protein 1 (MRP1)
New Dammarane-type Glycosides from the Roots of Gynostemma pentaphyllum
期刊论文
OAI收割
PLANTA MEDICA, 2012, 卷号: 78, 期号: 6, 页码: 597-605
作者:
Ma, Lei
;
Xiang, Wen-Juan
;
Pham Van Khang
;
Liang, Yang
;
Xiao, Yaping
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Gynostemma pentaphyllum
Cucurbitaceae
gypenoside
dammarane-type glycoside
saponins