中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
昆明植物研究所 [2]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2023 [1]
2022 [1]
2021 [1]
2015 [1]
2012 [1]
学科主题
Biochemist... [1]
Plant Scie... [1]
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Structurally diverse spirocyclic polycyclic polyprenylated acylphloroglucinols from Hypericum ascyron Linn. and their anti-tumor activity
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 212, 页码: 113727
作者:
Hu,Ya-Li
;
Yue,Grace Gar-Lee
;
Li,Xing-Ren
;
Xu,Gang
;
Lau,Clara Bik-San
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/07/25
Hypericaceae
Polycyclic polyprenylated acylphloroglucinols
Spirocyclic polyprenylated acylphloroglucinols
HCT116 cells
Zebrafish model
Hypericum ascyron Linn
NATURAL-PRODUCTS
A-H
DERIVATIVES
FLOWERS
VEGF
Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555
作者:
Li, Ennian
;
Wang, Kai
;
Zhang, Bei
;
Guo, Siqi
;
Xiao, Senhao
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2022/08/16
DNMT1 inhibitor
A549 cell lines
HCT116 cell lines
antitumor activity
pharmacokinetic
Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway
期刊论文
OAI收割
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
作者:
Yang,Hao-Jie
;
Li,Ya-Nan
;
Yan,Chen
;
Yang,Jue
;
Zeng,Yan-Rong
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2022/04/02
Dysoxylum gotadhora
Rocaglaol derivatives
HCT116
Cytotoxic activity
MAPK pathway
FLAVAGLINES
Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 4, 页码: 517-527
作者:
Ma, Yi-ming
;
Han, Wei
;
Li, Jia
;
Hu, Li-hong
;
Zhou, Yu-bo
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
physalin B
Physalis angulata L
HCT116 colon cancer cells
autophagy
reactive oxygen species
p38 mitogen-activated protein kinases
microtubule-associated proteins
apoptosis
ubiquitins
N-acetyl-L-cysteine
Characterization of dihydroartemisinin-resistant colon carcinoma HCT116/R cell line
期刊论文
OAI收割
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2012, 卷号: 360, 期号: 1-2, 页码: 329-337
作者:
Lu, Jin-Jian
;
Chen, Si-Meng
;
Ding, Jian
;
Meng, Ling-Hua
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Dihydroartemisinin
Resistant
Proteomics
Anti-tumor
HCT116