中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海生物化学与细胞生... [9]
上海药物研究所 [5]
昆明动物研究所 [3]
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期刊论文 [21]
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2024 [2]
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2017 [1]
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Design, Synthesis, and Bioevaluation of Transcriptional Enhanced Assocciated Domain (TEAD) PROTAC Degraders
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 5, 页码: 631-639
作者:
Li, Huajie
;
Ge, Zhiming
;
Lin, Kexin
;
He, Wei
;
Chu, Qinyu
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2024/06/27
Hippo pathway
TEAD
PROTAC
Selectivity
Regulation of hippo signaling mediated apoptosis by
Rauvolfia tetraphylla
in triple-negative breast cancer
期刊论文
OAI收割
MEDICAL ONCOLOGY, 2024, 卷号: 41, 期号: 5, 页码: 14
作者:
Balavaishnavi, B.
;
Kamaraj, M.
;
Nithya, T. G.
;
Santhosh, P.
;
Gokilalakshmi, S.
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/05/07
Anti-proliferative effect
Hippo pathway
MDA-MB-231 cells
Apoptosis
Rauvolfia tetraphylla
Electrochemically derived nanographene oxide activates endothelial tip cells and promotes angiogenesis by binding endogenous lysophosphatidic acid
期刊论文
OAI收割
BIOACTIVE MATERIALS, 2022, 卷号: 9, 页码: 92-104
作者:
Liu, Wenjing
;
Luo, Haiyun
;
Wei, Qinwei
;
Liu, Jia
;
Wu, Junrong
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/07/01
Nanographene oxide
Lysophosphatidic acid
Hydrogen bonding
Endothelial tip cell
Hippo signalling
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:
Lu, Tian
;
Li, Yong
;
Lu, Wenchao
;
Spitters, Twgm
;
Fang, Xueyu
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/12/01
Hippo pathway
TEAD3
Covalent inhibitor
Palmitoylation inhibitor
Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:
Lu, Wenchao
;
Wang, Jun
;
Li, Yong
;
Tao, Hongru
;
Xiong, Huan
  |  
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2020/07/01
Hippo pathway
TEAD transcription factor
Covalent inhibitor
Palmitoylation inhibitor
Cyclopeptide RA-V Inhibits Organ Enlargement and Tumorigenesis Induced by YAP Activation
期刊论文
OAI收割
CANCERS, 2018, 卷号: 10, 期号: 11
作者:
Ji, Xinyan
;
Song, Lihua
;
Sheng, Li
;
Gao, Anhui
;
Zhao, Yang
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
hippo pathway
YAP
TAZ
RA-V
cancer
organ size
protein synthesis
Targeting IRF3 as a YAP agonist therapy against gastric cancer
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL MEDICINE, 2018, 卷号: 215, 期号: 2, 页码: 699-718
作者:
Jiao, Shi
;
Guan, Jingmin
;
Chen, Min
;
Wang, Wenjia
;
Li, Chuanchuan
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/04/28
Hippo Signaling Pathway
Organ Size Control
Interferon Regulatory Factor-3
Minor Aphthous Ulceration
Cell Contact Inhibition
Tumor-suppressor
Innate Immunity
Growth-control
Intestinal Regeneration
Colorectal-cancer
PRDM4 mediates YAP-induced cell invasion by activating leukocyte-specific integrin beta 2 expression
期刊论文
OAI收割
EMBO REPORTS, 2018, 卷号: 19, 期号: 6, 页码: -
作者:
Liu, Huan
;
Dai, Xiaoming
;
Cao, Xiaolei
;
Yan, Huan
;
Ji, Xinyan
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/04/28
Yes-associated Protein
Histone Methyltransferase Complex
Hippo Signaling Pathway
Organ Size Control
Transcription Factor
Prostate-cancer
Tissue Homeostasis
Gene-expression
Growth-control
Myeloid Cells
Effects of High Blood Pressure on Cardiovascular Disease Events Among Chinese Adults With Different Glucose Metabolism
期刊论文
OAI收割
DIABETES CARE, 2018, 卷号: 41, 期号: 9, 页码: 1895-1900
作者:
Tian, Jingyan
;
Li, Wenyi
;
Wang, Weiqing
;
Sheng, Chang-Sheng
;
Sun, Weihong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/09
Canoe/Afadin
Hippo signalling
JNK signalling
Ras signalling
tumorigenesis
Hippo信号通路在乳腺癌中的调控机制及作用
期刊论文
OAI收割
遗传, 2017, 卷号: 39, 期号: 7, 页码: 617-629
作者:
雷群英
;
姚传波
;
陈策实
;
周鑫
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2017/08/04
Taz/yap
Hippo信号通路
乳腺癌