中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [4]
上海生物化学与细胞生... [3]
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OAI收割 [9]
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期刊论文 [9]
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2021 [1]
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2012 [1]
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Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52, 页码: 12
作者:
Ding, Hong
;
Pei, Yuan
;
Li, Yuanqing
;
Xu, Wen
;
Mei, Lianghe
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/06/15
Epigenetics
Histone acetyltransferase
P300/CBP
Ovarian cancer
Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20, 页码: 5397-5407
作者:
Lu, Wenchao
;
Xiong, Huan
;
Chen, Yu
;
Wang, Chen
;
Zhang, Hao
  |  
收藏
  |  
浏览/下载:146/0
  |  
提交时间:2019/01/08
Drug discovery
Epigenetics
Histone acetyltransferase
P300/CBP
Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 867-876
作者:
Zhang, Rukang
;
Wang, Jiang
;
Zhao, Liang
;
Liu, Shien
;
Du, Daohai
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
High throughput screening
Epigenetics
Histone acetyltransferase
MOF
Inhibitor
Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 740-751
作者:
Xiong, Huan
;
Han, Jie
;
Wang, Jun
;
Lu, Wenchao
;
Wang, Chen
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
Epigenetics
Histone acetyltransferase
GCN5
High throughput screening
1,8-Acridinedione derivative
Merge and separation of NuA4 and SWR1 complexes control cell fate plasticity in Candida albicans
期刊论文
OAI收割
CELL DISCOVERY, 2018, 卷号: 4, 期号: 1, 页码: 45
作者:
Wang, Xiongjun
;
Zhu, Wencheng
;
Chang, Peng
;
Wu, Hongyu
;
Chen, Jiangye
  |  
收藏
  |  
浏览/下载:95/0
  |  
提交时间:2019/04/28
Histone Variant H2a.z
Chromatin-remodeling Complex
Dna-damage Response
Yeats Domain
Saccharomyces-cerevisiae
Overlapping Functions
Acetyltransferase
Acetylation
Protein
Transcription
Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription
期刊论文
OAI收割
GENES & DEVELOPMENT, 2012, 卷号: 26, 期号: 12, 页码: 1376-1391
Qiu, Yu
;
Liu, Lei
;
Zhao, Chen
;
Han, Chuanchun
;
Li, Fudong
;
Zhang, Jiahai
;
Wang, Yan
;
Li, Guohong
;
李国红
;
Mei, Yide
;
Wu, Mian
;
Wu, Jihui
;
Shi, Yunyu
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2013/12/24
histone acetyltransferase
MOZ
PHD finger
H3R2me0
H3K14ac
HOXA9
Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2008, 卷号: 171, 期号: 1, 页码: 26-36
作者:
Chen, J
;
Du, CS
;
Kang, JH
;
Wang, JM
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2015/07/22
copper
pyrrolidine dithiocarbamate
histone acetylation
histone acetyltransferase
histone deacetylase
apoptosis
Reversible histone acetylation involved in transcriptional regulation of WT1 gene
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2007, 卷号: 39, 期号: 12, 页码: 931-938
作者:
Shao Yangguang
;
Lu Jun
;
Cheng Cao
;
Cui Liguo
;
Zhang Guoping
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/02/02
WILMS-TUMOR
ACETYLTRANSFERASE P300
DEACETYLASE
ENHANCER
PROTEIN
GATA-1
SP1
histone acetylation
WT1
HDAC
p300/CBP
transcriptional regulation
Histone hypoacetylation is involved in 1,10-phenanthroline-Cu2+-induced human hepatoma cell apoptosis
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2005, 卷号: 10, 期号: 2, 页码: 190-198
作者:
Kang, JH
;
Chen, J
;
Shi, YF
;
Jia, J
;
Wang, ZH
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2015/07/22
reactive oxygen species
histone hypoacetylation
1
histone acetyltransferase
histone deacetylase
10-orthophenanthroline