中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
长春应用化学研究所 [4]
力学研究所 [1]
大连化学物理研究所 [1]
上海生物化学与细胞生... [1]
生态环境研究中心 [1]
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OAI收割 [15]
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期刊论文 [13]
学位论文 [2]
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2023 [1]
2021 [1]
2018 [3]
2017 [1]
2015 [1]
2013 [1]
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学科主题
交叉与边缘领域的力学... [1]
超分子化学 [1]
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Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 19
作者:
Zhu, Shengnan
;
Yuan, Qingning
;
Li, Xinzhu
;
He, Xinheng
;
Shen, Shiyi
  |  
收藏
  |  
浏览/下载:214/0
  |  
提交时间:2024/01/16
different ligands
recognition
ligand selectivity
receptor
Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 32, 页码: 8
作者:
Wang, Xi
;
Cheng, Xi
;
Zhao, Lihua
;
Wang, Yuzhe
;
Ye, Chenyu
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/11/04
parathyroid hormone receptor 2
cryo-electron microscopy
G protein-coupled receptor
ligand recognition
syndromic short stature
Application of ITC-Based Characterization of Thermodynamic and Kinetic Association of Ligands With Proteins in Drug Design
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Su, Haixia
;
Xu, Yechun
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
ITC
thermodynamics
kinetics
protein-ligand recognition
drug design
Recent Trends and Applications of Molecular Modeling in GPCR-Ligand Recognition and Structure-Based Drug Design
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 7
作者:
Yuan, Xiaojing
;
Xu, Yechun
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
GPCR
receptor-ligand recognition
drug design
molecular modeling
molecular dynamics
docking
binding affinity
binding pathway
Structural Insights into the pH-Dependent Conformational Change and Collagen Recognition of the Human Mannose Receptor
期刊论文
OAI收割
STRUCTURE, 2018, 卷号: 26, 期号: 1, 页码: 60-+
作者:
Hu, Zhenzheng
;
Shi, Xiangyi
;
Yu, Bowen
;
Li, Na
;
Huang, Ying
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/04/28
Dendritic Cell-receptor
Cysteine-rich Domain
Carbohydrate-recognition
Ligand-binding
Electron-microscopy
Crystal-structure
Necrotic Cells
Complex
Model
Macrophages
雌激素受体α介导信号通路关键环节分子机制的计算研究
学位论文
OAI收割
北京: 中国科学院生态环境研究中心, 2017
作者:
曹慧明
  |  
收藏
  |  
浏览/下载:340/0
  |  
提交时间:2018/06/22
配体结合
雌激素受体α信号通路
分子动力学模拟
辅因招募
Erα-mediated Signaling Pathway
受体响应元件识别
Molecular Dynamics Simulations
Ligand Binding
Cofactor Recruitment
Ere Recognition
Structural Studies of G Protein-Coupled Receptors
期刊论文
OAI收割
MOLECULES AND CELLS, 2015, 卷号: 38, 期号: 10, 页码: 836-842
作者:
Zhang, Dandan
;
Zhao, Qiang
;
Wu, Beili
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
activation
allosteric modulation
GPCR
ligand recognition
structure
Optimizing Scoring Function of Protein-Nucleic Acid Interactions with Both Affinity and Specificity
期刊论文
OAI收割
plos one, 2013, 卷号: 8, 期号: 9, 页码: 文献号: e74443
Yan ZQ
;
Wang J
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2014/04/15
KNOWLEDGE-BASED POTENTIALS
COMPUTATIONAL REDESIGN
DOCKING BENCHMARK
MEAN FORCE
MOLECULAR RECOGNITION
BINDING-AFFINITY
DNA INTERACTIONS
ENERGY FUNCTION
LIGAND-BINDING
DATA-BANK
Tyrosine replacement of PSGL-1 reduces association kinetics with P- and L-selectin on the cell membrane
期刊论文
OAI收割
BIOPHYSICAL JOURNAL, 2012, 卷号: 103, 期号: 4, 页码: 777-785
作者:
Xiao BT(肖波涛)
;
Tong CF(佟春芳)
;
Jia XL(贾潇凌)
;
Guo R(郭瑞)
;
Lv SQ(吕守芹)
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2013/01/18
Ligand Binding-Kinetics
Glycoprotein Ligand-1
Molecular-Dynamics
Adhesion
Sulfation
Proteins
Glycosulfopeptides
Identification
Dissociation
Recognition
Tyrosine sulfation in N-terminal domain of human C5a receptor is necessary for binding of chemotaxis inhibitory protein of Staphylococcus aureus
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2011, 卷号: 32, 期号: 8, 页码: 1038
作者:
Liu Zhenjia
;
Yang Yanjuan
;
Jiang Lei
;
Xu Yingchun
;
Wang Aixia
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/24
CHEMOKINE RECEPTORS
LIGAND-BINDING
ANAPHYLATOXIN
RECOGNITION
RESIDUES
C5L2
Staphylococcus aureus
chemotaxis inhibitory protein
tyrosine sulfation
post-translational modification
chemotactic receptor
C5aR