中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
金属研究所 [265]
福建物质结构研究... [187]
长春应用化学研究... [149]
上海药物研究所 [127]
化学研究所 [113]
大连化学物理研究所 [83]
更多
采集方式
OAI收割 [1193]
iSwitch采集 [59]
内容类型
期刊论文 [1220]
学位论文 [19]
会议论文 [11]
CNKI期刊论文 [1]
SCI/SSCI论文 [1]
发表日期
2022 [16]
2021 [18]
2019 [26]
2018 [47]
2017 [37]
2016 [31]
更多
学科主题
Chemistry [23]
物理化学与绿色催化 [17]
Pharmacol... [13]
Biochemis... [12]
物理化学 [11]
Cell Biolo... [6]
更多
筛选
浏览/检索结果:
共1252条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
发表日期升序
发表日期降序
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
The effects of typical amino acid ligands on Cd translocation and detoxification processes in hyperaccumulator Sedum alfredii Hance
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL SCIENCES, 2026, 卷号: 164, 页码: 47-56
作者:
Kang, Fengxin
;
Wei, Rongfei
;
Huang, Xuzheng
;
Dawuda, Usman Kaku
;
Xu, Pei
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2026/04/16
Cadmium
Phytoremediation
Sedum alfredii
Amino acid
Organic ligand
Molecular basis for cross-activation of NPFF2R by a short PrRP-related peptide
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2026, 页码: 11
作者:
Li, Xin
;
Li, Shuai
;
Shan, Hong
;
Yuan, Qing-ning
;
He, Xin-heng
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/04/01
prolactin-releasing peptide
PrRPR
NPFF2R
ligand recognition
obesity therapy
Bidirectional Regulation between Metabolic Dysfunction-associated Steatotic Liver Disease and Sarcopenia via Liver-muscle Crosstalk
期刊论文
OAI收割
JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY, 2026, 页码: 16
作者:
Song, Yeyu
;
Liu, Yameng
;
Jiang, Jie
;
Zheng, Youjie
;
Wang, Zixuan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/04/01
Sarcopenia
Metabolic dysfunction-associated steatotic liver dis-ease
Mendelian randomization
Liver-muscle crosstalk
C-C motif chemokine ligand 2
Adrenomedullin
Dynamic-GLEP: a dynamics-informed deep learning framework for ligand efficacy prediction in representative Class A GPCRs
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2026, 卷号: 27, 期号: 1, 页码: 15
作者:
Chen, Zhiyi
;
Hao, Yongxin
;
Su, Yuhong
;
Agren, Hans
;
Chen, Mingan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/04/01
GPCR ligand efficacy
molecular dynamics
conformational ensembles
deep learning
structure-based drug design
transfer learning
Dual-sensitization nanoformulation combining glutamine metabolism inhibition and Fas/FasL activation for enhanced colorectal cancer immunotherapy
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2025, 卷号: 388, 页码: 14
作者:
Yan, Dan
;
Yi, Wenzhe
;
Wu, Ting
;
Hu, Shuangshuang
;
Ding, Yan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
Glutamine inhibition
Engineered immune cells
Fas ligand
Immunotherapy
Colorectal cancer
Advancing active compound discovery for novel drug targets: insights from AI-driven approaches
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12
作者:
Wang, Xing-you
;
Chen, Yang
;
Li, Yu-fan
;
Wei, Chao-yang
;
Liu, Meng-ya
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/08/20
AI-driven drug discovery
novel drug targets
molecular design
ligand exploration
phenotypic drug discovery
undruggable targets
Native Ligand-Inspired peptides for c-MET targeted PET probes development
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2025, 页码: 18
作者:
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/08/20
C-MET
Native ligand
HGF
PET/CT imaging
Radiopharmaceuticals
Peptide probes
Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8
作者:
Wang, Shi-hang
;
Zeng, Yue
;
Yang, Hao
;
Tian, Si-yuan
;
Zhou, Yong-qi
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2025/07/25
N
-methyl-
D
-aspartate receptors
GluN1/GluN3A
ligand-based virtual screening
scaffold hopping
deep learning
GeminiMol
Discovery of multi-chitinase inhibitors cinnamyl thiazolidinone compounds as candidates for insect growth regulators via ligand-based optimization strategies
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 306, 页码: 14
作者:
Jiang, Zhiyang
;
Shi, Dongmei
;
Fu, Haoyu
;
Li, Yan
;
Zou, Renxuan
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2025/05/27
Multi-chitinase inhibitor
Cinnamaldehyde compounds
Thiazolidinone compounds
Ligand-based optimization
Insect growth regulators (IGRs)
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors