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Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  
Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载:44/0  |  提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
Preparation of (R)-2-chloro-1-(m-chlorophenyl)ethanol by Lipozyme TL IM-catalyzed second resolution 期刊论文  OAI收割
CHINESE CHEMICAL LETTERS, 2012, 卷号: 23, 期号: 3, 页码: 289-292
Xia, Shi Wen; Lin, Hui; Chen, Yong Zheng
收藏  |  浏览/下载:27/0  |  提交时间:2013/07/03
北斗卫星导航系统可靠性工作若干问题探讨 会议论文  OAI收割
第二届中国卫星导航学术年会
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收藏  |  浏览/下载:94/0  |  提交时间:2016/06/04
3R intersection target positioning in real time based on distance (EI CONFERENCE) 会议论文  OAI收割
2010 International Conference on Computer, Mechatronics, Control and Electronic Engineering, CMCE 2010, August 24, 2010 - August 26, 2010, Changchun, China
Nengwei W.; Juan C.; Jian C.
收藏  |  浏览/下载:13/0  |  提交时间:2013/03/25
The positioning error based on angle  angle-distance or single station positioning increases with the distance increasing. 3R target positioning based on distance can obtain the high precision measurements in long distance. Here we give the 3R model for the intersection positioning  provide the two necessary conditions for getting the optimum intersection point. The experimental results show that the intersection precision based on angle is over 2m and will degrade greatly with the increasing of distance while the one based on 3R model will improve and the error decrease gradually. That the precision of the distance measurement is about 1m means the 3R model is better than the angle positioning  which can compensate the drawbacks of the angle positioning at short distance. 2010 IEEE.  
Characteristics of ZnMgO-based metal-semiconductor-metal photodetectors (EI CONFERENCE) 会议论文  OAI收割
International Symposium on Photoelectronic Detection and Imaging, ISPDI 2007: Photoelectronic Imaging and Detection, September 9, 2007 - September 12, 2007, Beijing, China
作者:  
Zhang J.;  Li B.;  Li B.;  Li B.;  Zhao Y.
收藏  |  浏览/下载:23/0  |  提交时间:2013/03/25
In recent years  ZnMgO semiconductor alloys  with a direct bandgap tunable between 3.37 eV and 7.8 eV  become one of the most suitable materials for the fabrication of ultraviolet detectors. In this paper  we have fabricated metal-semiconductor-metal photodetectors on 1-m thick Zn 0.8Mg0.2O films. The interdigital metal electrodes are 500 m long and 5 m wide with an interelectrode spacing 2 m  5 m and 10 m  respectively. Zn0.8Mg0.2O films were grown on quartz by ratio frequency magnetron sputtering at 500C. Dark current  spectral responsivity and pulse response were carried out for the devices with different finger pitches. All the photodetectors showed the peak responsivity at 330 nm and the ultraviolet-visible rejection ratio (R330 nm/R400 nm) is more than four orders of magnitude at 3 V bias. For the device with 2 m finger pitch  the detectivity was calculated as 4.21011 cm Hz 1/2/W at 330 nm. Furthermore  the transient response measurement for all devices revealed similar rise time of 10 ns. The 90%-10% fall times are 130 ns  170 ns and 230 ns for the devices with different finger pitches of 2 m  5 m and 10 m  respectively..  
Vibrational spectra of cis and trans m-fluorostyrene in the S-1 state studied by one color resonant two photon ionization and theoretical calculations 期刊论文  OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2006, 卷号: 794, 期号: 1-3, 页码: 320-327
作者:  
Huang, Jiangou;  Xiao, Daoqing;  Bi, Weibin;  Xu, Xiling;  Gao, Zhen
  |  收藏  |  浏览/下载:25/0  |  提交时间:2019/04/09
Vibrational spectra of cis and trans m-fluorostyrene in the S-1 state studied by one color resonant two photon ionization and theoretical calculations 期刊论文  OAI收割
journal of molecular structure, 2006, 卷号: 794, 期号: 1-3, 页码: 320-327
作者:  
Huang, Jiangou;  Xiao, Daoqing;  Bi, Weibin;  Xu, Xiling;  Gao, Zhen
收藏  |  浏览/下载:19/0  |  提交时间:2015/11/11
Comparison of structure and electrochemistry of Al- and Fe-doped LiNi1/3Co1/3Mn1/3O2 期刊论文  OAI收割
ELECTROCHIMICA ACTA, 2006, 卷号: 51, 期号: 20, 页码: 4199
Liu, DT; Wang, ZX; Chen, LQ
收藏  |  浏览/下载:18/0  |  提交时间:2013/09/17
M/M^r/1/N排队系统 期刊论文  OAI收割
应用概率统计, 1993, 卷号: 9.0, 期号: 003, 页码: 266-270
作者:  
何启明
  |  收藏  |  浏览/下载:2/0  |  提交时间:2021/01/14