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长春光学精密机械与物... [2]
物理研究所 [1]
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数学与系统科学研究院 [1]
大连化学物理研究所 [1]
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期刊论文 [6]
会议论文 [3]
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2013 [1]
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Chemistry [1]
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Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells
期刊论文
OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:
Zeng, Guang-Zhi
;
Fan, Jun-Ting
;
Xu, Jun-Ju
;
Li, Yan
;
Tan, Ning-Hua
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)
one of the major components isolated from the traditional
Chinese medicine Rubia yunnanensis
exhibited inhibitory activity on the proliferation of several
human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay
and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle
arrest in human cervical carcinoma HeLa cells. Further
MTA was found to induce apoptosis of HeLa cells
through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and
release of cytochrome c into the cytosol
which caused the cleavage of caspase and poly(ADP-ribose)
polymerase and finally triggered the apoptosis. Furthermore
the p53/p21/Cdc2-cyclin B1 signaling was
found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of
cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused
the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of
R. yunnanensis
a folk anti-cancer herb used in Yunnan
China.
Preparation of (R)-2-chloro-1-(m-chlorophenyl)ethanol by Lipozyme TL IM-catalyzed second resolution
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2012, 卷号: 23, 期号: 3, 页码: 289-292
Xia, Shi Wen
;
Lin, Hui
;
Chen, Yong Zheng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2013/07/03
(R)-2-Chloro-1-(m-chlorophenyl)ethanol
LipozymeTL IM
Enzymatic transesterification
Vinyl acetate
Second resolution
北斗卫星导航系统可靠性工作若干问题探讨
会议论文
OAI收割
第二届中国卫星导航学术年会
-
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2016/06/04
卫星导航系统
可靠性保证
3R-2V-1M
3R intersection target positioning in real time based on distance (EI CONFERENCE)
会议论文
OAI收割
2010 International Conference on Computer, Mechatronics, Control and Electronic Engineering, CMCE 2010, August 24, 2010 - August 26, 2010, Changchun, China
Nengwei W.
;
Juan C.
;
Jian C.
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2013/03/25
The positioning error based on angle
angle-distance or single station positioning increases with the distance increasing. 3R target positioning based on distance can obtain the high precision measurements in long distance. Here we give the 3R model for the intersection positioning
provide the two necessary conditions for getting the optimum intersection point. The experimental results show that the intersection precision based on angle is over 2m and will degrade greatly with the increasing of distance while the one based on 3R model will improve and the error decrease gradually. That the precision of the distance measurement is about 1m means the 3R model is better than the angle positioning
which can compensate the drawbacks of the angle positioning at short distance. 2010 IEEE.
Characteristics of ZnMgO-based metal-semiconductor-metal photodetectors (EI CONFERENCE)
会议论文
OAI收割
International Symposium on Photoelectronic Detection and Imaging, ISPDI 2007: Photoelectronic Imaging and Detection, September 9, 2007 - September 12, 2007, Beijing, China
作者:
Zhang J.
;
Li B.
;
Li B.
;
Li B.
;
Zhao Y.
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  |  
浏览/下载:23/0
  |  
提交时间:2013/03/25
In recent years
ZnMgO semiconductor alloys
with a direct bandgap tunable between 3.37 eV and 7.8 eV
become one of the most suitable materials for the fabrication of ultraviolet detectors. In this paper
we have fabricated metal-semiconductor-metal photodetectors on 1-m thick Zn 0.8Mg0.2O films. The interdigital metal electrodes are 500 m long and 5 m wide with an interelectrode spacing 2 m
5 m and 10 m
respectively. Zn0.8Mg0.2O films were grown on quartz by ratio frequency magnetron sputtering at 500C. Dark current
spectral responsivity and pulse response were carried out for the devices with different finger pitches. All the photodetectors showed the peak responsivity at 330 nm and the ultraviolet-visible rejection ratio (R330 nm/R400 nm) is more than four orders of magnitude at 3 V bias. For the device with 2 m finger pitch
the detectivity was calculated as 4.21011 cm Hz 1/2/W at 330 nm. Furthermore
the transient response measurement for all devices revealed similar rise time of 10 ns. The 90%-10% fall times are 130 ns
170 ns and 230 ns for the devices with different finger pitches of 2 m
5 m and 10 m
respectively..
Vibrational spectra of cis and trans m-fluorostyrene in the S-1 state studied by one color resonant two photon ionization and theoretical calculations
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2006, 卷号: 794, 期号: 1-3, 页码: 320-327
作者:
Huang, Jiangou
;
Xiao, Daoqing
;
Bi, Weibin
;
Xu, Xiling
;
Gao, Zhen
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/04/09
M-fluorostyrene
Vibrational Spectrum
Ab Initio
Density Functional Theory (Dft)
One Color Resonant Two Photon Ionization (1c-r2pi)
Vibrational spectra of cis and trans m-fluorostyrene in the S-1 state studied by one color resonant two photon ionization and theoretical calculations
期刊论文
OAI收割
journal of molecular structure, 2006, 卷号: 794, 期号: 1-3, 页码: 320-327
作者:
Huang, Jiangou
;
Xiao, Daoqing
;
Bi, Weibin
;
Xu, Xiling
;
Gao, Zhen
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2015/11/11
m-fluorostyrene
vibrational spectrum
ab initio
density functional theory (DFT)
one color resonant two photon ionization (1C-R2PI)
Comparison of structure and electrochemistry of Al- and Fe-doped LiNi1/3Co1/3Mn1/3O2
期刊论文
OAI收割
ELECTROCHIMICA ACTA, 2006, 卷号: 51, 期号: 20, 页码: 4199
Liu, DT
;
Wang, ZX
;
Chen, LQ
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2013/09/17
LITHIUM-ION BATTERIES
SOLID-STATE CHEMISTRY
INSERTION MATERIAL
CATHODE MATERIALS
LICO1/3NI1/3MN1/3O2
R(3)OVER-BAR-M
LICOO2
M/M^r/1/N排队系统
期刊论文
OAI收割
应用概率统计, 1993, 卷号: 9.0, 期号: 003, 页码: 266-270
作者:
何启明
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2021/01/14
排队系统
M/M^r/1/M
队长平稳分布