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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
高能物理研究所 [1]
重庆绿色智能技术研究... [1]
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OAI收割 [5]
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期刊论文 [5]
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2022 [1]
2021 [1]
2020 [1]
2018 [1]
2017 [1]
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The p-n heterojunction-engineered Bi2MoO6/KNbO3 with 2D/3D architecture for enhanced photocatalytic activity towards benzene-containing contaminants under visible light illumination
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 2022, 卷号: 10, 期号: 5, 页码: 13
作者:
Liu, Chen
;
He, Xi
;
Fan, Yuhan
;
Li, Jun
;
He, Xinxia
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/10/14
Multi-targeted removal
Benzene-containing contaminants
2D/3D p-n heterojunction
Photocatalytic
Visible light
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
OAI收割
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
No pulsed radio emission during a bursting phase of a Galactic magnetar
期刊论文
OAI收割
Nature, 2020, 卷号: 587, 页码: 63-65
作者:
HXMT
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/02/08
Astrophysics - High Energy Astrophysical Phenomena
Abstract: Fast radio bursts (FRBs) are millisecond-duration radio transients of unknown physical origin observed at extragalactic distances
1-3
. It has long been speculated that magnetars are the engine powering repeating bursts from FRB sources
4-13
, but no convincing evidence has been collected so far
14
. Recently, the Galactic magnetar SRG 1935+2154 entered an active phase by emitting intense soft íray bursts
15
. One FRB-like event with two peaks (FRB 200428) and a luminosity slightly lower than the faintest extragalactic FRBs was detected from the source, in association with a soft íray/hard-X-ray flare
18-21
. Here we report an eight-hour targeted radio observational campaign comprising four sessions and assisted by multi-wavelength (optical and hard-X-ray) data. During the third session, 29 soft-íray repeater (SGR) bursts were detected in íray energies. Throughout the observing period, we detected no single dispersed pulsed emission coincident with the arrivals of SGR bursts, but unfortunately we were not observing when the FRB was detected. The non-detection places a fluence upper limit that is eight orders of magnitude lower than the fluence of FRB 200428. Our results suggest that FRB-SGR burst associations are rare. FRBs may be highly relativistic and geometrically beamed, or FRB-like events associated with SGR bursts may have narrow spectra and characteristic frequencies outside the observed band. It is also possible that the physical conditions required to achieve coherent radiation in SGR bursts are difficult to satisfy, and that only under extreme conditions could an FRB be associated with an SGR burst.
Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 428-441
作者:
Zhang, Qiumeng
;
Shen, Qianqian
;
Gao, Lixin
;
Tong, Linjiang
;
Li, Jia
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
Aurora A
Aurora B
KDR
Multi-targeted
Anticancer
Heterocyclic
evaluationofinvitroandinvivoactivityofamultityrosinekinaseinhibitoral3810againsthumanthyroidcancer
期刊论文
OAI收割
actapharmacologicasinica, 2017, 卷号: 38, 期号: 11, 页码: 1533
作者:
Xie Qin
;
Chen Hui
;
Al Jing
;
Gao Yinglei
;
Geng Meiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
TARGETED THERAPIES
RET
CARCINOMA
MODELS
GROWTH
TUMORS
CELLS
thyroid cancer
AL3810
multi-tyrosine kinases inhibitor
angiogenesis
RET