中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
长春应用化学研究所 [16]
新疆理化技术研究所 [15]
上海药物研究所 [13]
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期刊论文 [91]
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Risk of drug-drug interactions in China's fight against COVID-19 and beyond
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 196, 页码: 2
作者:
Zhang, Qingpeng
;
Yang, Jiannan
;
Zeng, Daniel Dajun
;
Feng, Yibin
;
Wong, Ian C. K.
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/26
Drug interactions
Protein-protein interactions
Network science
COVID-19
NMR and Patch-Clamp Characterization of Yeast Mitochondrial Pyruvate Carrier Complexes
期刊论文
OAI收割
biomolecules, 2023
作者:
Zhen Wang
;
Wen Ding
;
Maosen Ruan
;
Yong Liu
;
Jing Yang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/11/11
Mpc
PRE
NMR
patch-clamp
oligomeric state
protein interactions
Construction of stable membranal CMTM6-PD-L1 full-length complex to evaluate the PD-1/PD-L1-CMTM6 interaction and develop anti-tumor anti-CMTM6 nanobody
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Jia, Xiao-min
;
Long, Yi-ru
;
Yu, Xiao-lu
;
Chen, Run-qiu
;
Gong, Li-kun
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
cancer immunotherapy
CMTM6
CMTM6
PD-L1 complex
protein interactions
anti-CMTM6 nanobody
Structure-based design of a novel inhibitor of the ZIKA virus NS2B/ NS3 protease
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7
作者:
Xiong, Yanchao
;
Cheng, Fei
;
Zhang, Junyi
;
Su, Haixia
;
Hu, Hangchen
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/11/11
Zika virus
Fragment -based hit screening
Protein -inhibitor interactions
NS2B
NS3 protease
Crystal structure
蓖麻脂滴蛋白的结构与功能分析
学位论文
OAI收割
: 中国科学院大学, 2022
作者:
巩宇豪
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/14
脂滴蛋白,蛋白质相互作用,油脂,脂滴,蓖麻,种子
lipid droplet protein, protein-protein interactions, lipid, lipid droplets, castor bean, seed
SSGraphCPI: A Novel Model for Predicting Compound-Protein Interactions Based on Deep Learning
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 7, 页码: 13
作者:
Wang, Xun
;
Liu, Jiali
;
Zhang, Chaogang
;
Wang, Shudong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/12/07
deep learning
compound-protein interactions
compound properties
protein preperties
IC50 value
Membrane-Mediated Interactions Between Protein Inclusions
期刊论文
OAI收割
FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 卷号: 8, 页码: 11
作者:
Gao, Jie
;
Hou, Ruihan
;
Li, Long
;
Hu, Jinglei
;
Li L(李龙)
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/03/05
lipid membrane
protein inclusions
membrane-mediated interactions
nanoparticles
membrane elasticity
molecular dynamics
Monte Carlo
Drug design targeting active posttranslational modification protein isoforms
期刊论文
OAI收割
MEDICINAL RESEARCH REVIEWS, 2021, 卷号: 41, 期号: 3, 页码: 1701-1750
作者:
Meng, Fanwang
;
Liang, Zhongjie
;
Zhao, Kehao
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/22
Allosteric Inhibitor
Covalent Inhibitor
Posttranslational Modifications
Precision Medicine
Protac Protein Degradation
Protein‐
Protein Interactions
Ptm Protein Isoforms
Rational Drug Design
Self-Assembling Proteins for Design of Anticancer Nanodrugs
期刊论文
OAI收割
CHEMISTRY-AN ASIAN JOURNAL, 2020, 页码: 16
作者:
Zou, Qianli
;
Chang, Rui
;
Yan, Xuehai
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/05/21
Protein
Self-assembly
Intermolecular interactions
Nanodrugs
Cancer therapy
Combining High Speed ELM Learning with a Deep Convolutional Neural Network Feature Encoding for Predicting Protein-RNA Interactions
期刊论文
OAI收割
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 3, 页码: 972-980
作者:
Wang, L (Wang, Lei)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Huang, DS (Huang, De-Shuang)[ 3 ]
;
Zhou, FF (Zhou, Fengfeng)[ 4,5 ]
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/09
Proteins
RNA
Convolution
Neural networks
Benchmark testing
Feature extraction
Sparse matrices
Convolution neural network
extreme learning machine
RNA-protein interactions
sequence