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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共764条，第1-10条 帮助

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Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:  Liang, Xuewu;  Yu, Haolan;  Liang, Renwen;  Feng, Zhuanghui;  Saidahmatov, Abdusaid
  |  收藏  |  浏览/下载：15/0  |  提交时间：2024/04/09
Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17
作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu
  |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun
  |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26
Design, Synthesis, and Pharmacological Evaluation of Isoindoline Analogues as New HPK1 Inhibitors 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 23, 页码: 16201-16221
作者:  Xie, Chenghu;  Liu, Bo;  Song, Zilan;  Yang, Ye;  Dai, Mengdi
  |  收藏  |  浏览/下载：17/0  |  提交时间：2024/02/27
Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18
作者:  Zhang, Junjie;  Li, Yan;  Tang, Haotian;  Zhou, Qianqian;  Tong, Linjiang
  |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08
Two new compounds from the Hainan Soft Corals Sinularia tumulosa and Sinularia depressa with their anti-inflammatory or cytotoxic activities 期刊论文  OAI收割
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023, 卷号: 25, 期号: 10, 页码: 949-956
作者:  Xu, Ting;  Yu, Dan-Dan;  Su, Ming-Zhi;  Yao, Li-Gong;  Li, Song-Wei
  |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27
Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF) 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12
作者:  Wu, Xinyu;  Wang, Mingchen;  Cao, Yu;  Xu, Ying;  Yang, Ziqun
  |  收藏  |  浏览/下载：2/0  |  提交时间：2024/02/27
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines 期刊论文  OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14
作者:  Xu, Zhuo;  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Zhu, Mengying
  |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17
Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18
作者:  Ren, Pengxuan;  Li, Hui;  Nie, Tianqing;  Jian, Xiaoqin;  Yu, Changyue
  |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17
Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23
作者:  Li, Xuemei;  Wang, Peipei;  Wang, Chang;  Jin, Tingting;  Xu, Ran
  |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17