中国科学院机构知识库网格系统: 检索

Current approaches of nanomedicines in the market and various stage of clinical translation 期刊论文 OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 7, 页码: 3028-3048
作者: Shan, Xiaoting; Gong, Xiang; Li, Jie; Wen, Jingyuan; Li, Yaping

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Nanomedicines Nanoparticles Liposomes Vaccines Marketed products Clinical translations Disease-driven design Quality by design

Advanced astigmatism-corrected tandem Wadsworth mounting for small-scale spectral broadband imaging spectrometer (EI CONFERENCE) 会议论文 OAI收割
作者: Lin G.-Y.

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Tandem gratings of double-dispersion mount make it possible to design an imaging spectrometer for the weak light observation with high spatial resolution high spectral resolution and high optical transmission efficiency. The traditional tandem Wadsworth mounting is originally designed to match the coaxial telescope and large-scale imaging spectrometer. When it is used to connect the off-axis telescope such as off-axis parabolic mirror it presents lower imaging quality than to connect the coaxial telescope. It may also introduce interference among the detector and the optical elements as it is applied to the short focal length and small-scale spectrometer in a close volume by satellite. An advanced tandem Wadsworth mounting has been investigated to deal with the situation. The Wadsworth astigmatism-corrected mounting condition for which is expressed as the distance between the second concave grating and the imaging plane is calculated. Then the optimum arrangement for the first plane grating and the second concave grating which make the anterior Wadsworth condition fulfilling each wavelength is analyzed by the geometric and first order differential calculation. These two arrangements comprise the advanced Wadsworth mounting condition. The spectral resolution has also been calculated by these conditions. An example designed by the optimum theory proves that the advanced tandem Wadsworth mounting performs excellently in spectral broadband. 2012 Optical Society of America.

The electromagnetic compatibility design of restrained image transmission equipments (EI CONFERENCE) 会议论文 OAI收割
2011 3rd International Conference on Mechanical and Electronics Engineering, ICMEE 2011, September 23, 2011 - September 25, 2011, Hefei, China
作者: Wang W.; Wang W.

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In order to improve the quality of image transmission this paper puts forward a box shielding method that could eliminate electromagnetic interference signal on image transmission equipments. At first this paper analyzes the shielding effectiveness of electromagnetic interference selects the qualified shielding material and designs the structure. After that it analyzes the descending of shielding effectiveness in the operational system and improves the equipments shielding effectiveness by means of the electromagnetic compatibility design that accords with electromagnetic compatibility norms. At last through the EMI radiometry this paper confirms that the equipments are in accordance with the design requirements of electromagnetic compatibility norms. (2012) Trans Tech Publications Switzerland.

Space optical remote sensor of the CAE thermal control index calculation method (EI CONFERENCE) 会议论文 OAI收割
2011 International Conference on Advanced Design and Manufacturing Engineering, ADME 2011, September 16, 2011 - September 18, 2011, Guangzhou, China
作者: Li L.

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The thermal control indicators CAE methods of Space optical remote sensor are analyzed in the presented work. We sat up a thermal optical analysis model for space optical remote sensor. By assuming fully covered by in-orbit temperature load and using the finite element method for thermal deformation analysis we obtained the optical remote sensor surface deformation and displacement under various thermal loading. Using ZERNIKE polynomial wave was fitted to obtain ZERNIKE polynomial coefficients which were incorporated into the optical system design. Using CODE V optical calculation software heat-ray machines under elastic deformation of the system point spread function transfer function (MTF) wave front differential (WFE) etc. were calculated. Image quality changes of remote sensors are discussed in variety assumed cases such as temperature loads of quality change. By repeated iteration critical value of temperature fields meeting the design requirements are obtained for the optical system. Optical indicators were converged to the temperature field indicator then reasonable indicators of thermal control for remote sensors were obtained. For the thermal control design this method provided a reliable basis for design. (2011) Trans Tech Publications Switzerland.

Research on lightweight outer baffle for coaxial space camera (EI CONFERENCE) 会议论文 OAI收割
2011 International Conference on Electronic and Mechanical Engineering and Information Technology, EMEIT 2011, August 12, 2011 - August 14, 2011, Harbin, China
作者: Zhang L.; Zhang L.

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Stray light is non-imaging light that reach the optical system imaging plane. The non-imaging light can be received by detector if it is not effectively controlled and stray light which directly irradiates on the detector has great influence on the imaging quality. Stray light can be effectively inhibited if the outer baffle of space camera is designed optimally. Carbon fiber composite material is chosen as main material to meet requirements of a coaxial space optical system. The outer baffle should have advantages such as lightweight high stiffness and dimensional stability etc. Using optimization design tools the lightweight outer baffle is designed. And finite element method is used to check the structure. Development and test results show that the outer baffle with a diameter of 620mm and a total length of 1200mm only weighs 7.3kg. And the baffle's natural frequency reaches 88Hz and it can satisfy the requirements of the space camera. 2011 IEEE.

Design of driving circuit for binocular CCD image system (EI CONFERENCE) 会议论文 OAI收割
5th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Optoelectronic Materials and Devices for Detector, Imager, Display, and Energy Conversion Technology, April 26, 2010 - April 29, 2010, Dalian, China
作者: Zhang X.; Zhang X.; Zhang X.

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The paper designs a driving circuit of high sensitive wide dynamic and high signal-to-noise ratio for binocular CCD imaging system which adopts a Dalsa-made high resolution full-frame 33-mega pixels area CCD FTF5066M. Inner structure and driving timing of the FTF5066M sensor are presented. Field Programmable Gate Array (FPGA) is used as the main device to accomplish the timing design of the circuits and power driver control of the two sensors. By using the Correlated Double Sampling (CDS) technique the video noise is reduced and the SNR of the system is increased. A 12- bit A/D converter is used to improve the image quality. The output rate of the imaging system designed with integrated chip can reach to 1.3 frames per second through bi-channel. For its good performance low power consumption and small volume the driving system can be applied to aeronautics and astronautics field. With a further improvement a maximum data output rate of 2.7 frames per second can be reached through all the eight channels of the two CCDs. 2010 Copyright SPIE - The International Society for Optical Engineering.

High precision test method for dynamic imaging of space camera (EI CONFERENCE) 会议论文 OAI收割
2010 IEEE International Conference on Advanced Computer Control, ICACC 2010, March 27, 2010 - March 29, 2010, 445 Hoes Lane - P.O.Box 1331, Piscataway, NJ 08855-1331, United States
作者: Jin L.-X.; Zhang K.; Zhang K.; Zhang K.; Zhang K.

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A test method for dynamic imaging of space TDICCD (Time Delay and Integration Charge Coupled Devices) camera was presented in this paper. The test method adopted the PLL (Phase Locked Loop) technology and CMAC (Cerebella Model Articulation Controller) friction compensation as control strategy. Furthermore According to this method a test system for dynamic imaging of space TDICCD camera was designed and implemented. The system simulated the movement of the ground objects relative to the space aerocraft to validate the capability of image speed match and the dynamic imaging quality of TDICCD camera. The design adopted a precision turntable and a drift turntable to simulate the movement around the earth and the drift motion in different latitude due to the rotation of earth of the aerocraft. The turntables were drived by permanent magnet torque motor which was powered by PWM (Pulse Width Modulation). The system adopted DSP (Digital Signal Processor) as the control core and reached a very high performance. The experimental results showed that the steady speed error was better than 0.01 % and the instantaneous speed error reached 0.0267%. The precision of the test system designed met the requirement for dynamic imaging of TDICCD camera. 2010 IEEE.

Research on the the device of non-angular vibration for opto-electronic platform (EI CONFERENCE) 会议论文 OAI收割
5th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Smart Structures and Materials in Manufacturing and Testing, April 26, 2010 - April 29, 2010, Dalian, China
An Y.; Song C.-P.; Kuang R.-J.; Jin G.

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The opto-electronic platform is the main equipment for aviation reconnaissance. It is a surveillance system with the function of search recognition orientation and tracking by opto- electronic instruments. It is made up of opto-electronic instruments which are used to get high quality image and stabilization tracking system to control stabilization and gesture of platform for exact tracking. The opto-electronic platform purpose is to achieve high quality image. Besides the impact of optic system the image quality of the system is influenced greatly in the vibration environment. The research worked by Zhao peng which demonstrated the affection caused by angular vibration was worse than which caused by line vibration and what was multiplied direct ratio with plane altitude. So it is necessary to design a new device which could be used widely and has good angular vibration isolation effect. According to the theory of parallelogram the non-angular vibration device had been designed with spatial links and the theory of non-angular vibration was analyzed. The three-dimensional model was set with UG the analysis was done by ADAMS/vibration software. The acceleration and displacement response of the device in each direction was calculated by inspiriting it with sine wave of the acceleration in three directions and the stiffness and damp were studied. All the work prove the design principle of the device is reasonable and the device is adopted to keep the platform motion moving horizontally at the meantime the device is good at isolating vibration in all directions. 2010 SPIE.

Study of three-mode parametric instability (EI CONFERENCE) 会议论文 OAI收割
8th Edoardo Amaldi Conference on Gravitational Waves, June 21, 2009 - June 26, 2009, New York, NY, United states
Liang F.; Zhao C.; Gras S.; Ju L.; Blair G.

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The effect of parametric instability in advanced interferometric gravitational wave detectors is a potential problem for their proper operation. Great efforts have been made to study the onset of parametric instabilities and to find ways to control them. Here we present an experimental design for studying parametric instability in a 72 m cavity with suspended high quality fused silica mirrors. With 5 W input power and 20 kW circulation power inside the cavity it is predicted that parametric instability will occur. The resonant condition of parametric instability can be met by thermally tuning the radius of curvature of a test mass. We will present simulation results of parametric gains for different radii of curvature of a test mass. The simulation results will provide the basis for designing the thermal tuning and observation parametric instability experiments. This will provide a test bed for studying parametric instability and its control for next generation detectors. 2010 IOP Publishing Ltd.

Thermal difference analysis and athermalization design of infrared optical system (EI CONFERENCE) 会议论文 OAI收割
Optical Design and Testing IV, October 18, 2010 - October 20, 2010, Beijing, China
作者: Zhang X.; Zhang X.; Zhang X.

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When infrared optical system works in a large temperature range the thermal effect of optical lens and optical tube will produce image plane shift and lead to imaging quality deterioration. In order to eliminate the thermal aberration the athermalization design principles of infrared optical system were introduced and some commonly used methods of thermal difference compensation were described. Proceeding from single lens the thermal difference caused by temperature changing was analyzed and the relationship between temperature and focus shift was obtained. Considering optical tube thermal expansion a set of equations to estimate the thermal difference of lens group was given. Finally an infrared optical imaging system that can work under the temperature range of -40C to 60C was design according to athermal technique in which a new mechanical passive temperature compensation was proposed. Through simulation the athermalization design could make imaging plane shift the smallest. The simulation results coincided with the theoretical formula and the design had reference value in engineering. 2010 Copyright SPIE - The International Society for Optical Engineering.