中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
大连化学物理研究所 [2]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2023 [1]
2018 [1]
2017 [1]
2006 [2]
学科主题
Biochemist... [1]
Biophysics [1]
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Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
;
Zhu, Guanghao
;
Sun, Mengru
;
Zou, Kun
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity
Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2018, 卷号: 77, 页码: 320-329
作者:
Zou, Li-Wei
;
Weng, Zi-Miao
;
Ge, Guang-Bo
;
Dou, Tong-Yi
;
Wang, Ping
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/06/20
Flavonoids
Human Carboxylesterase 2 (Hce2)
Structure-inhibition Relationships
Selectivity
Inhibition Mechanism
Structure-activity relationships of flavonoids as natural inhibitors against E. coli beta-glucuronidase
期刊论文
OAI收割
FOOD AND CHEMICAL TOXICOLOGY, 2017, 卷号: 109, 页码: 975-983
作者:
Wu, Da-Chang
;
Zou, Li-Wei
;
Dou, Tong-Yi
;
Yang, Ling
;
Zhang, Tong-Yan
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/06/20
Flavonoids
E. Coli bE.a-glucuronidasE.
Structure-inhibition Relationships
Scutellarein
Luteolin
Investigation of the role of cytochrome P4502B4 active site residues in substrate metabolism based on crystal structures of the ligand-bound enzyme
期刊论文
OAI收割
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2006, 卷号: 455, 期号: 1, 页码: 61-67
作者:
Hernandez, Cynthia E.
;
Kumar, Santosh
;
Liu, Hong
;
Halpert, James R.
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
cytochrome P450
structure function relationships
site-directed mutagenesis
enzyme catalysis and inhibition
P450 2134 crystal structure