机构

• 上海药物研究所 [8]
• 大连化学物理研究所 [2]
• 生物物理研究所 [1]
• 化学研究所 [1]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2025 [2]
• 2024 [3]
• 2022 [1]
• 2017 [2]
• 2014 [2]
• 2012 [1]
• 更多

学科主题

• Biochemica... [1]
• 物理化学 [1]

筛选

浏览/检索结果: 共13条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17 作者:  Hu, Linghao;  Xu, Hesong;  Xu, Ye;  Chen, Haowen;  Jiang, Hanrui   |  收藏  |  浏览/下载：13/0  |  提交时间：2025/04/01 NSD2  RE-IIBP  Targeted protein degradation  Multiple myeloma   Fibroblast activation protein peptide-targeted NIR-I/II fluorescence imaging for stable and functional detection of hepatocellular carcinoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2025, 页码: 14 作者:  Lin, En;  Song, Miaomiao;  Wang, Bo;  Shi, Xiaojing;  Zhao, Jiali   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/04/01 Hepatocellular carcinoma  Cancer-associated fibroblasts  Fibroblast activation protein  Near-infrared fluorescence  Peptide-targeted fluorescence imaging   An overview of PROTACs targeting MDM2 as a novel approach for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 8 作者:  Li, Huiwen;  Cai, Xinhui;  Yang, Xiaoyu;  Zhang, Xuan   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/09/26 MDM2  PROTAC  p53  MDMX  Targeted protein degradation   Accelerating PROTACs Discovery Through a Direct-to-Biology Platform Enabled by Modular Photoclick Chemistry 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 12 作者:  Yan, Ke-Nian;  Nie, Yong-Qiang;  Wang, Jia-Yu;  Yin, Guang-Liang;  Liu, Qia   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/05/31 High-throughput chemical synthesis  modular synthesis  photoclick chemistry  PROTACs library  targeted protein degradation   Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12 作者:  Zou, Zhi-feng;  Yang, Lei;  Nie, Hui-jun;  Gao, Jing;  Lei, Shu-min   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/05/22 proteolysis-targeting chimeras  tumor-targeted delivery  precise protein degradation  combination therapy  triple-negative breast cancer   Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2022, 卷号: 10 作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/12/23 targeted protein degradation  PROTAC  molecular glue  chemically induced proximity  drug discovery and development   Hyaluronic acid modification of RNase A and its intracellular delivery using lipid-like nanoparticles 期刊论文  OAI收割 JOURNAL OF CONTROLLED RELEASE, 2017, 卷号: 263, 页码: 39-45 作者:  Wang, Xiaoying;  Li, Yamin;  Li, Quanshun;  Neufeld, Caleb I.;  Pouli, Dimitra   |  收藏  |  浏览/下载：70/0  |  提交时间：2018/06/15 Targeted Protein Delivery  Lipidoids  Protein Engineering  Cd44  Hyaluronic Acid   Glioma Dual-Targeting Nanohybrid Protein Toxin Constructed by Intein-Mediated Site-Specific Ligation for Multistage Booster Delivery 期刊论文  OAI收割 THERANOSTICS, 2017, 卷号: 7, 期号: 14, 页码: 3489-3503 作者:  Chen, Yingzhi;  Zhang, Meng;  Jin, Hongyue;  Li, Dongdong;  Xu, Fan   |  收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 trichosanthin  lactoferrin  brain targeted delivery  antiglioma therapy  MMP-2  intein-mediated protein ligation  cell-penetrating peptide   Orally active-targeted drug delivery systems for proteins and peptides 期刊论文  OAI收割 EXPERT OPINION ON DRUG DELIVERY, 2014, 卷号: 11, 期号: 9, 页码: 1435-1447 作者:  Li, Xiuying;  Yu, Miaorong;  Fan, Weiwei;  Gan, Yong;  Hovgaard, Lars   |  收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 active-targeted drug delivery systems  IgG-Fc receptor  intercellular adhesion molecule-1  oral protein and peptide delivery  proton-coupled folate transporter  recombinant fusion protein  transferrin receptor   Multi-state Targeting Machinery Govern the Fidelity and Efficiency of Protein Localization 期刊论文  OAI收割 protein conformational dynamics, 2014, 卷号: 805, 页码: 385-409 作者:  Yang, Mingjun;  Pang, Xueqin;  Han, Keli;  Han, KL;  Zhang, X 收藏  |  浏览/下载：29/0  |  提交时间：2015/11/17 Signal recognition particle  Protein targeting  Protein localization  Molecular machinery  Protein machinery  Protein conformational dynamics  Principal component analysis  Targeted molecular dynamics