机构

• 上海药物研究所 [26]
• 合肥物质科学研究院 [7]
• 上海生物化学与细胞生... [6]
• 中国科学院大学 [5]
• 昆明植物研究所 [3]
• 青岛生物能源与过程研... [3]
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采集方式

• OAI收割 [62]
• iSwitch采集 [6]

内容类型

• 期刊论文 [66]
• 学位论文 [2]

发表日期

• 2024 [2]
• 2023 [9]
• 2022 [10]
• 2021 [9]
• 2020 [1]
• 2019 [2]
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学科主题

• Cell Biolo... [4]
• Science & ... [3]
• 生物资源::代谢物组... [2]
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• Environmen... [1]
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筛选

浏览/检索结果: 共68条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486 作者:  Chang, Qi;  Li, Jiayi;  Deng, Yue;  Zhou, Ruilin;  Wang, Bingwei   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 Role of F-box proteins in human upper gastrointestinal tumors 期刊论文  OAI收割 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2024, 卷号: 1879, 期号: 1, 页码: 16 作者:  Zhang, Che;  Pan, Guangzhao;  Qin, Jiang-Jiang   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/02/27 F-box protein  Upper gastrointestinal cancer  E3 ubiquitin ligase  Ubiquitin   The new direction of drug development: Degradation of undruggable targets through targeting chimera technology 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54 作者:  Liang, Xuewu;  Ren, Hairu;  Han, Fengyang;  Liang, Renwen;  Zhao, Jiayan   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/01/16 chimeric design  degradation System  PROTAC  targeted degradation technology  undruggable targets   Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells 期刊论文  OAI收割 LIFE SCIENCES, 2023, 卷号: 332, 页码: 10 作者:  Su, Ai-Ling;  Tian, Chang-Qing;  Ou, Ying-Jie;  Bao, Xu-Bin;  Huan, Xia-Juan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 CD73  Proteasome inhibitors  ERK  NSCLC   Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17 作者:  Zeng, Yanping;  Xiao, Jian;  Xu, Yuanxin;  Wei, Fan;  Tian, Lina   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17 Discovery of HyT-Based Degraders of CDK9-Cyclin T1 Complex 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2023, 页码: 10 作者:  Lin, Rongkun;  Yang, Jie;  Liu, Ting;  Wang, Mingyu;  Ke, Chongrong   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 CDK9  cyclin T1  degrader  hydrophobic tag  protein degradation   Recent Advances in Pro-PROTAC Development to Address On-Target Off-Tumor Toxicity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 13 作者:  Chen, Chuanjie;  Yang, Yiwen;  Wang, Zhe;  Li, Huiwen;  Dong, Chanjuan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 17 作者:  Yan, Ziqin;  Lyu, Xilin;  Lin, Dongze;  Wu, Gaoxing;  Gong, Yang   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/10/17 Stimuli-activatable PROTACs for precise protein degradation and cancer therapy 期刊论文  OAI收割 SCIENCE BULLETIN, 2023, 卷号: 68, 期号: 10, 页码: 1069-1085 作者:  Gao, Jing;  Yang, Lei;  Lei, Shumin;  Zhou, Feng;  Nie, Huijun   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 PROTAC  Stimuli-activatable prodrug  Precise protein degradation  Nanomedicine  Combinatory therapy   E3 ligase ligand optimization of Clinical PROTACs 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2023, 卷号: 11, 页码: 15 作者:  Jiang, Hanrui;  Xiong, Huan;  Gu, Shuang-Xi;  Wang, Mingliang   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/04/10 PROTACs  E3 ubiquitin ligase ligand  structure optimization  clinical trials  CRBN