中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
合肥物质科学研究院 [1]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2025 [4]
2024 [3]
2022 [1]
学科主题
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浏览/检索结果:
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Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 15
作者:
Xu, Yali
;
Hu, Hao
;
Ran, Yu
;
Zhao, Wensi
;
Guo, An-Di
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Chemoproteomics
Molecular glue degraders
Photo-crosslinking
Protein-protein interactions
Targeted protein degradation
Unveiling p65 as the target of diphyllin in ameliorating metabolic dysfunction-associated steatotic liver disease via targeted protein degradation technology
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2025, 卷号: 16, 页码: 12
作者:
Zhu, Xuejing
;
Zhang, Lei
;
Cui, Wenqian
;
Wang, Liangjie
;
Xu, Fengjing
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/07/25
metabolic dysfunction-associated steatotic liver disease
diphyllin
p65
targeted protein degradation technology
NRF2
Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 13
作者:
Xu, Yali
;
Zhao, Wensi
;
Nie, Hui-Jun
;
Wang, Jiamin
;
Fu, Jingjing
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/05/27
Chemoproteomics
Genetic code expansion
Molecular glue degrader
Photo-crosslinking
Targeted protein degradation
Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17
作者:
Hu, Linghao
;
Xu, Hesong
;
Xu, Ye
;
Chen, Haowen
;
Jiang, Hanrui
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/04/01
NSD2
RE-IIBP
Targeted protein degradation
Multiple myeloma
An overview of PROTACs targeting MDM2 as a novel approach for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 8
作者:
Li, Huiwen
;
Cai, Xinhui
;
Yang, Xiaoyu
;
Zhang, Xuan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/09/26
MDM2
PROTAC
p53
MDMX
Targeted protein degradation
Accelerating PROTACs Discovery Through a Direct-to-Biology Platform Enabled by Modular Photoclick Chemistry
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 12
作者:
Yan, Ke-Nian
;
Nie, Yong-Qiang
;
Wang, Jia-Yu
;
Yin, Guang-Liang
;
Liu, Qia
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/05/31
High-throughput chemical synthesis
modular synthesis
photoclick chemistry
PROTACs library
targeted protein degradation
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Key Considerations in Targeted Protein Degradation Drug Discovery and Development
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:
Qin, Liena
;
Dai, Han
;
Wang, Junfeng
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/12/23
targeted protein degradation
PROTAC
molecular glue
chemically induced proximity
drug discovery and development