机构

• 上海药物研究所 [8]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [9]

内容类型

• 期刊论文 [9]

发表日期

• 2025 [5]
• 2024 [3]
• 2022 [1]

学科主题

筛选

浏览/检索结果: 共9条，第1-9条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Rational engineering of degradation tail-driven CELMoD-antibody conjugates for precision malignancy therapy 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 12, 页码: 6510-6528 作者:  Guo, Yu;  Song, Yi;  Wang, Hanlin;  Lu, Yang;  Zhang, Jingyu   |  收藏  |  浏览/下载：0/0  |  提交时间：2026/01/29 Degrader-antibody conjugate  Antibody-drug conjugate  Cereblon E3 ligase modulator  Immunomodulatory drug  Molecular glue  Targeted protein degradation  Multiple myeloma  Hematologic malignancy   Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 15 作者:  Xu, Yali;  Hu, Hao;  Ran, Yu;  Zhao, Wensi;  Guo, An-Di   |  收藏  |  浏览/下载：21/0  |  提交时间：2025/08/20 Chemoproteomics  Molecular glue degraders  Photo-crosslinking  Protein-protein interactions  Targeted protein degradation   Unveiling p65 as the target of diphyllin in ameliorating metabolic dysfunction-associated steatotic liver disease via targeted protein degradation technology 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2025, 卷号: 16, 页码: 12 作者:  Zhu, Xuejing   |  收藏  |  浏览/下载：23/0  |  提交时间：2025/07/25 metabolic dysfunction-associated steatotic liver disease  diphyllin  p65  targeted protein degradation technology  NRF2   Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 13 作者:  Xu, Yali;  Zhao, Wensi;  Nie, Hui-Jun;  Wang, Jiamin;  Fu, Jingjing   |  收藏  |  浏览/下载：50/0  |  提交时间：2025/05/27 Chemoproteomics  Genetic code expansion  Molecular glue degrader  Photo-crosslinking  Targeted protein degradation   Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17 作者:  Hu, Linghao;  Xu, Hesong;  Xu, Ye;  Chen, Haowen;  Jiang, Hanrui   |  收藏  |  浏览/下载：45/0  |  提交时间：2025/04/01 NSD2  RE-IIBP  Targeted protein degradation  Multiple myeloma   An overview of PROTACs targeting MDM2 as a novel approach for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 8 作者:  Li, Huiwen;  Cai, Xinhui   |  收藏  |  浏览/下载：46/0  |  提交时间：2024/09/26 MDM2  PROTAC  p53  MDMX  Targeted protein degradation   Accelerating PROTACs Discovery Through a Direct-to-Biology Platform Enabled by Modular Photoclick Chemistry 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 12 作者:  Yan, Ke-Nian;  Nie, Yong-Qiang;  Wang, Jia-Yu;  Yin, Guang-Liang;  Liu, Qia   |  收藏  |  浏览/下载：67/0  |  提交时间：2024/05/31 High-throughput chemical synthesis  modular synthesis  photoclick chemistry  PROTACs library  targeted protein degradation   Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12 作者:  Zou, Zhi-feng;  Yang, Lei;  Nie, Hui-jun;  Gao, Jing;  Lei, Shu-min   |  收藏  |  浏览/下载：48/0  |  提交时间：2024/05/22 proteolysis-targeting chimeras  tumor-targeted delivery  precise protein degradation  combination therapy  triple-negative breast cancer   Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2022, 卷号: 10 作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng   |  收藏  |  浏览/下载：76/0  |  提交时间：2022/12/23 targeted protein degradation  PROTAC  molecular glue  chemically induced proximity  drug discovery and development