中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
合肥物质科学研究院 [1]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2025 [1]
2024 [3]
2022 [1]
学科主题
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Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17
作者:
Hu, Linghao
;
Xu, Hesong
;
Xu, Ye
;
Chen, Haowen
;
Jiang, Hanrui
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
NSD2
RE-IIBP
Targeted protein degradation
Multiple myeloma
An overview of PROTACs targeting MDM2 as a novel approach for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 8
作者:
Li, Huiwen
;
Cai, Xinhui
;
Yang, Xiaoyu
;
Zhang, Xuan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/09/26
MDM2
PROTAC
p53
MDMX
Targeted protein degradation
Accelerating PROTACs Discovery Through a Direct-to-Biology Platform Enabled by Modular Photoclick Chemistry
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 12
作者:
Yan, Ke-Nian
;
Nie, Yong-Qiang
;
Wang, Jia-Yu
;
Yin, Guang-Liang
;
Liu, Qia
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/05/31
High-throughput chemical synthesis
modular synthesis
photoclick chemistry
PROTACs library
targeted protein degradation
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Key Considerations in Targeted Protein Degradation Drug Discovery and Development
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:
Qin, Liena
;
Dai, Han
;
Wang, Junfeng
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/12/23
targeted protein degradation
PROTAC
molecular glue
chemically induced proximity
drug discovery and development