中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
金属研究所 [1]
化学研究所 [1]
数学与系统科学研究院 [1]
西北高原生物研究所 [1]
合肥物质科学研究院 [1]
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OAI收割 [12]
内容类型
期刊论文 [11]
学位论文 [1]
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2025 [1]
2024 [1]
2022 [1]
2021 [1]
2020 [1]
2013 [1]
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学科主题
药物分析 [1]
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Sorafenib resistance and therapeutic strategies in hepatocellular carcinoma
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2025, 卷号: 1880, 期号: 3, 页码: 17
作者:
Zhang, Weijing
;
Hong, Xuechuan
;
Xiao, Yuling
;
Wang, Hongbo
;
Zeng, Xiaodong
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/06/23
Hepatocellular carcinoma
Sorafenib
Drug resistance
Therapeutic strategy
Nanotechnology used for siRNA delivery for the treatment of neurodegenerative diseases: Focusing on Alzheimer's disease and Parkinson's disease
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2024, 卷号: 666, 页码: 15
作者:
Li, Yan
;
Zhang, Jiahui
;
Ma, Boqin
;
Yu, Wenjun
;
Xu, Meixia
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/11/26
Neurodegenerative diseases
Brain drug delivery
Therapeutic drug
Small interfering RNA
Nanotechnology
Therapeutic drug monitoring of caffeine and its primary metabolites in plasma using LC-ESI-MS/MS for apnea of prematurity treatment: Evaluation of ultrapure water as a surrogate matrix
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2022, 卷号: 36, 期号: 11, 页码: e5462
作者:
Long, Jia-Yi
;
Hu, Ya-Hui
;
Xia, Ying
;
Du, Fei-Fei
;
Dai, Hao-Ran
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/03/21
apnea of prematurity
caffeine
LC-ESI-MS
MS
preterm infants
surrogate matrix
therapeutic drug monitoring
A nanoselenium-coating biomimetic cytomembrane nanoplatform for mitochondrial targeted chemotherapy- and chemodynamic therapy through manganese and doxorubicin codelivery
期刊论文
OAI收割
JOURNAL OF NANOBIOTECHNOLOGY, 2021, 卷号: 19
作者:
Xiao, Jianmin
  |  
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2021/08/30
Cell membrane
Reactive oxygen species
Superoxide dismutase-1
Glutathione peroxidase 4
Dual-mode therapeutic pathways
Drug delivery system
Therapy for Apnoea of Prematurity: A Retrospective Study on Effects of Standard Dose and Genetic Variability on Clinical Response to Caffeine Citrate in Chinese Preterm Infants
期刊论文
OAI收割
ADVANCES IN THERAPY, 2020, 页码: 20
作者:
He, Xin
;
Qiu, Jin-Chun
;
Lu, Ke-Yu
;
Guo, Hong-Li
;
Li, Ling
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
Adenosine receptors
AHR
AOP
Caffeine
Phosphodiesterase
Polymorphism
Therapeutic drug monitoring
Discovery of a selective Na(V)1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 卷号: 110, 期号: 43, 页码: 17534-17539
作者:
Yang SL
;
Xiao Y
;
Kang D
;
Liu J
;
Li Y
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2013/11/25
chronic pain
drug discovery
peptide therapeutic
Kernel-based data fusion improves the drug-protein interaction prediction
期刊论文
OAI收割
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2011, 卷号: 35, 期号: 6, 页码: 353-362
作者:
Wang, Yong-Cui
;
Zhang, Chun-Hua
;
Deng, Nai-Yang
;
Wang, Yong
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2018/07/30
Drug-target interaction
Chemical space
Pharmacological space
Therapeutic space
Genomic space
Kernel function
Support vector machine
Kernel-based data fusion improves the drug-protein interaction prediction
期刊论文
OAI收割
computational biology and chemistry, 2011, 卷号: 35, 期号: 6, 页码: 353-362
作者:
Wang, Yong-Cui
;
Zhang, Chun-Hua
;
Deng, Nai-Yang
;
Wang, Yong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2017/06/30
Drug-target interaction
Chemical space
Pharmacological space
Therapeutic space
Genomic space
Kernel function
Support vector machine
Towards structure-based protein drug design
期刊论文
OAI收割
BIOCHEMICAL SOCIETY TRANSACTIONS, 2011, 卷号: 39, 页码: 1382-1386
作者:
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/04/09
Computational Design
De Nova Design
Grafting
Protein Drug
Protein-protein Docking
Protein Therapeutic
Reversion of Multidrug-Resistance by Proteasome Inhibitor Bortezomib in K562/DNR Cell Line
期刊论文
OAI收割
CHINESE JOURNAL OF CANCER RESEARCH, 2011, 卷号: 23, 期号: 1, 页码: 69-73
作者:
Wang Huihan
;
Li Yingchun
;
Liao Aijun
;
Fu Beibei
;
Yang Wei
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/02/26
MULTIPLE-MYELOMA CELLS
FACTOR-KAPPA-B
CHEMOTHERAPEUTIC-AGENTS
THERAPEUTIC TARGET
DRUG-RESISTANCE
P-GLYCOPROTEIN
LEUKEMIA
CANCER
MALIGNANCIES
SENSITIVITY
Bortezomib
NF-kappa B
Multi-drug resistance
mdr1 gene
P-gp
K562 cells