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浏览/检索结果: 共472条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Developmental biology of the Ediacaran Megaclonophycus from the Weng'an Biota 期刊论文  OAI收割 BIOLOGY LETTERS, 2026, 卷号: 22, 期号: 3, 页码: 8 作者:  Flett, Kirsten E.;  Cracknell, Kelsie;  Yamahuchi, Johnny S. Clavo;  Cunningham, John A.;  Zhu, Maoyan（朱茂炎）   |  收藏  |  浏览/下载：1/0  |  提交时间：2026/04/20 developmental biology  Ediacaran  Weng'an biota  Doushantuo Formation  Megaclonophycus  affinity  synchrotron tomography   Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML) 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17 作者:  Mo, Jun;  Wang, Yuxian;  Pan, Youlu;  Xiao, Qitao;  Zhao, Jinyi   |  收藏  |  浏览/下载：37/0  |  提交时间：2025/08/20 Menin  High binding affinity  Anti-proliferation activity  AML   Identification of small-molecule inhibitors for GluN1/GluN3A NMDA receptors via a multiscale CNN-based prediction model 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9 作者:  Han, Li;  Zeng, Yue;  Qu, Zhi-yan;  Fang, Sui;  Wang, Hai-ying   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/12/04 N-methyl-D-aspartate receptors  GluN1/GluN3A  drug-target binding affinity  convolutional neural networks  ImageDTA  virtual screening   Alkaline phosphatase-coupled high affinity phosphate transporters were involved in low phosphorus stress responding in Pyropia yezoensis 期刊论文  OAI收割 ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2025, 卷号: 90, 页码: 11 作者:  Gao, Xianrong;  Tian, Chao;  Wang, Shurui;  Guo, Menglin;  Niu, Jianfeng   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/08/22 Pyropia yezoensis  Alkaline phosphatase  High-affinity symporter  Pi-starvation  Myb-transcription factor  Dissolved organic phosphorus   Discovery of a ubiquitin-specific protease 10 inhibitor with high binding affinity promoting cell apoptosis via down-regulated CDK4 for the treatment of hepatocellular carcinoma 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 17 作者:  Lu, Yang;  Wang, Wentao;  Yuan, Cheng;  Luo, Mengxin;  Wang, Peipei   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/12/04 HCC  USP10  Deubiquitination  Binding affinity  CDK4   Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13 作者:  Li, Kun;  Zeng, Yue;  Xiong, Yi-da;  Wu, Hao-chen;  Fang, Sui   |  收藏  |  浏览/下载：32/0  |  提交时间：2025/08/20 drug-target affinity prediction  virtual screening  contrastive learning  graph neural network  N-methyl-D-aspartate (NMDA) receptors  GluN3A subunit.   Enhanced antibody-mediated cellular cytotoxicity of germline-like anti-HER2 antibodies through a point mutation in complementarity-determining regions 期刊论文  OAI收割 JOURNAL OF IMMUNOLOGY, 2025, 页码: 11 作者:  Zhou, Guangyu;  Zhang, Yunsen;  Gu, Yuheng;  Cao, Bihui;  Fan, Xin   |  收藏  |  浏览/下载：45/0  |  提交时间：2025/06/23 affinity maturation  antibody-mediated cellular cytotoxicity  gremlin-like antibody  HER2  in silicon   Drug Target Investigation of N-p-Coumaroyl-N'-Caffeoylputrescine, a Naturally-Occurring Alkaloid Derived from Saxifraga tangutica 期刊论文  OAI收割 ANTIOXIDANTS, 2025, 卷号: 14, 期号: 1 作者:  Liu, Chuang;  Dang, Jun;  Wu, Minchen   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/11/27 Saxifraga tangutica  N-p-coumaroyl-N'-caffeoylputrescine  drug affinity responsive target stability  reverse virtual docking  molecular dynamics simulation   Online bioactivity-guided HPLC-lipoprotein lipase system with medium-high pressure chromatography for rapid recognition and targeted isolation of natural affinity agents from Nitraria tangutorum 期刊论文  OAI收割 JOURNAL OF CHROMATOGRAPHY A, 2025, 卷号: 1762 作者:  Wu, Qianyu;  Zhang, Yu;  Sun, Ce;  Dang, Jun   |  收藏  |  浏览/下载：13/0  |  提交时间：2025/11/27 Nitraria tangutorum  Online HPLC-lipoprotein lipase system  Lipoprotein lipase active chromatographic peak recognition  Medium-high pressure liquid chromatography  Lipoprotein lipase affinity agents   Interaction-Based Inductive Bias in Graph Neural Networks: Enhancing Protein-Ligand Binding Affinity Predictions From 3D Structures 期刊论文  OAI收割 IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2024, 卷号: 46, 期号: 12, 页码: 8191-8208 作者:  Yang, Ziduo;  Zhong, Weihe;  Lv, Qiujie;  Dong, Tiejun;  Chen, Guanxing   |  收藏  |  浏览/下载：56/0  |  提交时间：2025/01/14 Proteins  Programmable logic arrays  Three-dimensional displays  Predictive models  Graph neural networks  Data models  Convolution  Protein-ligand binding affinity  graph neural networks  inductive bias  drug-target interaction  structure-based virtual screening