中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Chemoenzymatic liquid-phase synthesis and immunogenic assessment of tumor-associated complex MUC1 glycopeptide variants
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 302, 页码: 11
作者:
Teng, Changcai
;
Ma, Wenjing
;
Liu, Jinfeng
;
Hou, Juan
;
Zhang, Yalong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
MUC1 glycopeptide conjugate
Liquid phase glycopeptide synthesis
Immunological evaluations
Development of a bispecific antibody-drug conjugate targeting EpCAM and CLDN3 for the treatment of multiple solid tumors
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 16
作者:
Luo, Meiying
;
Wang, Xiaohuan
;
Yu, Guoji
;
Ji, Jing
;
Li, Long
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/07
EpCAM
CLDN3
Antibody-drug conjugate
Dxd
Solid tumor
Quantifying the sustainability of human and natural systems: A novel perspective on conjugate mechanisms
期刊论文
OAI收割
ENVIRONMENTAL IMPACT ASSESSMENT REVIEW, 2025, 卷号: 112, 页码: 107792
作者:
Gao, Qian
;
Tang, Danling
;
Liu, Haimeng
;
Wang, Changjian
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/03/18
Human and natural systems
Sustainability
Conjugate mechanisms
Urban agglomeration
Tianshan Mountains
Design and synthesis of novel site-specific antibody-drug conjugates that target TROP2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 110, 页码: 16
作者:
Luo, Caili
;
Ren, Anni
;
Jin, Zixuan
;
Zhang, Jianxin
;
Shi, Wei
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/22
TROP2
Antibody-drug conjugate (ADC)
Site-specific
Glycoengineering
Affinity-directed conjugation
Epigenetic Reprogramming Potentiates ICAM1 Antibody Drug Conjugates in Preclinical Models of Melanoma
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 卷号: 11
作者:
Zhang, Peng
;
Tao, Changjuan
;
Lu, Ye
;
Li, Peijing
;
Wang, Xing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/11/20
antibody drug conjugate
decitabine
ICAM1
melanoma
targeted therapy
Development of an ELISA with acidification treatment for an antibody conjugate incorporating Exatecans
期刊论文
OAI收割
ANALYTICAL BIOCHEMISTRY, 2024, 卷号: 690, 页码: 8
作者:
Zhang, Yingying
;
Yun, Xi
;
Ouyang, Lu
;
Zhang, Xianjing
;
Gong, Likum
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/06/27
Antibody-drug conjugate
Camptothecin
Exatecan
Bioanalysis
Pharmacokinetics
Low molecular weight chitosan based GSH-responsive self-assembled cationic micelle with enhanced anti-tumor effect by combining oxidative damage and chemotherapy
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 268, 页码: 12
作者:
Yuan, Yuting
;
Chen, Qiuhong
;
Wang, Zhenhua
;
Mi, Yingqi
;
Dong, Fang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/10/24
Amphiphilic conjugate
GSH-responsive cationic micelle
Low molecular weight chitosan
Adenosine-modulating synthetic high-density lipoprotein for chemoimmunotherapy of triple-negative breast cancer
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 367, 页码: 637-648
作者:
Gong, Xiang
;
Zheng, Chao
;
Cai, Ying
;
Zhang, Wen
;
Zhu, Binyu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/07
Peptide-drug conjugate
Synthetic high-density lipoprotein
Adenosine
Immunogenic cell death
Immunosuppression
Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14
作者:
Tao, Yimin
;
Lu, Wei
;
Gao, Jinli
;
Yang, Shuangshuang
;
Ruan, Chaoyi
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/03/13
antibody-drug conjugate (ADC)
bioanalysis
anti-drug antibody (ADA)
ligand binding assay (LBA)
ADA-tolerant assay
Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS
期刊论文
OAI收割
XENOBIOTICA, 2024, 页码: 9
作者:
Yuan, Yali
;
Wang, Weiqiang
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/02/19
peptide-drug conjugate
PDC
LN005
metabolite identification
liver S9s