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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
大连化学物理研究所 [11]
上海药物研究所 [2]
武汉物理与数学研究所 [1]
武汉植物园 [1]
天津工业生物技术研究... [1]
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OAI收割 [15]
iSwitch采集 [1]
内容类型
期刊论文 [16]
发表日期
2023 [1]
2019 [2]
2018 [2]
2016 [2]
2014 [1]
2013 [2]
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学科主题
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Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:
Lu, Shiwei
;
Zhang, Feng
;
Gong, Jiahao
;
Huang, Jian
;
Zhu, Guanghao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/12/08
Cytochrome P450 3A4 (CYP3A4)
Inhibitors
Isoquinoline chalcones
Orally active
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
作者:
Ma, Hong-Ping
;
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/06/20
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
Cytochrome p450 3a enzymes are key contributors for hepatic metabolism of bufotalin, a natural constitute in chinese medicine chansu
期刊论文
iSwitch采集
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 10
作者:
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
;
Zhang, Feng
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2019/05/08
Bufotalin
Cytochrome p450 3a (cyp3a)
Hydroxylation
Human liver microsomes (hlms)
Docking simulations
Discovery of a non-stereoselective cytochrome P450 catalyzing either 8 alpha- or 8 beta-hydroxylation of germacrene A acid from the Chinese medicinal plant, Inula hupehensis
期刊论文
OAI收割
PLANT JOURNAL, 2018, 卷号: 93, 期号: 1, 页码: 92-106
作者:
Gou, Junbo
;
Hao, Fuhua
;
Huang, Chongyang
;
Kwon, Moonhyuk
;
Chen, Fangfang
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2018/12/29
C12
8-fused STLs
cytochrome P450 (CYP)
germacrene A acid C8-hydroxylase
Inula hupehensis
inunolide
sesquiterpene lactones (STLs)
Discovery of a non-stereoselective cytochrome P450 catalyzing either 8 alpha- or 8 beta-hydroxylation of germacrene A acid from the Chinese medicinal plant, Inula hupehensis
期刊论文
OAI收割
PLANT JOURNAL, 2018, 卷号: 93, 期号: 1, 页码: 92-106
作者:
Zhang, Yansheng
;
Kwon, Moonhyuk
;
Huang, Chongyang
;
Hao, Fuhua
;
Gou, Junbo
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2018/11/05
C12
8-fused Stls
Cytochrome P450 (Cyp)
Germacrene a Acid C8-hydroxylase
Inula Hupehensis
Inunolide
Sesquiterpene Lactones (Stls)
Oxidation of Cucurbitadienol Catalyzed by CYP87D18 in the Biosynthesis of Mogrosides from Siraitia grosvenorii
期刊论文
OAI收割
PLANT AND CELL PHYSIOLOGY, 2016, 卷号: 57, 期号: 5, 页码: 1000-1007
作者:
Zhang, Jiangsheng
;
Dai, Longhai
;
Yang, Jiangang
;
Liu, Can
;
Men, Yan
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2017/03/21
Cucurbitadienol
CYP87D18
Cytochrome P450
Mogrosides
Siraitia grosvenorii
Cytochrome P450 promiscuity leads to a bifurcating biosynthetic pathway for tanshinones
期刊论文
OAI收割
NEW PHYTOLOGIST, 2016, 卷号: 210, 期号: 2, 页码: 525-534
作者:
Cui, Guanghong
;
Guo, Juan
;
Ma, Xiaohui
;
Cai, Yuan
;
Ma, Ying
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/06/20
Cytochrome P450 (Cyp) Monooxygenases
Diterpenoid Biosynthesis
Enzymatic Promiscuity
Metabolic Pathways
Salvia Miltiorrhiza Bunge
Synthetic Biology
Inhibitory Effects of 17 Steroids Towards 6 Major Cytochrome P450 Isoforms
期刊论文
OAI收割
latin american journal of pharmacy, 2014, 卷号: 33, 期号: 8, 页码: 1326-1331
作者:
Wang, Guo-En
;
Cao, Yun-Feng
;
Kurihara, Hiroshi
;
Fang, Zhong-Ze
;
He, Rong-Rong
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2015/11/17
Cytochrome P450 (CYP)
In vivo drug-drug interaction (DDI)
Steroids
Investigation of the in Vitro Metabolism of Evodiamine: Characterization of Metabolites and Involved Cytochrome P450 Isoforms
期刊论文
OAI收割
phytotherapy research, 2013, 卷号: 27, 期号: 5, 页码: 705-712
作者:
Sun, Hong-Zhi
;
Fang, Zhong-Ze
;
Cao, Yun-Feng
;
Sun, Xiao-Yu
;
Hong, Mo
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2015/11/09
evodiamine
cytochrome P450 (CYP)
human liver microsomes (HLMs)
In Silico Prediction of Cytochrome P450-Mediated Site of Metabolism (SOM)
期刊论文
OAI收割
PROTEIN AND PEPTIDE LETTERS, 2013, 卷号: 20, 期号: 3, 页码: 279-289
作者:
Liu, Xian
;
Shen, Qiancheng
;
Li, Jing
;
Li, Shanshan
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
ADME
computational method
CYP
cytochrome P450
SOM