中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [22]
海洋研究所 [7]
南海海洋研究所 [6]
生态环境研究中心 [6]
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期刊论文 [56]
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Pharmacokinetics, mass balance, and metabolism of [
14
C]envonalkib (TQ-B3139), a novel ALK tyrosine kinase inhibitor, in healthy Chinese subjects
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2024, 页码: 11
作者:
Ma, Sheng
;
Wang, Xin
;
Yan, Shu
;
Miao, Liyan
;
Wan, Xiaojing
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/05/07
Envonalkib
TQ-B3139
Pharmacokinetics
Mass balance
Excretion
Metabolism
Novel NIR-II fluorescent probes for biliary atresia imaging
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 11, 页码: 4578-4590
作者:
Zeng, Xiaodong
;
Liao, Yuqin
;
Qiao, Xue
;
Liang, Ke
;
Luo, Qiusi
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2024/01/16
Biliary atresia
Fluorescence imaging
Second near-infrared window
Early diagnosis
Hepatobiliary excretion
Development and validation of LC-MS/MS method for quantitation of sodium oligomannate in human plasma, urine and feces
期刊论文
OAI收割
BIOANALYSIS, 2023, 卷号: 15, 期号: 7, 页码: 371-390
作者:
Zhang, Zhenqing
;
Yang, Xing
;
Zhang, Lu
;
Zhu, Haizhong
;
Huang, Biao
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/27
Alzheimer's disease
excretion
LC-MS/MS
pharmacokinetics
phase I clinical trial
sodium oligomannate
Biotic and Abiotic Transformation Pathways of a Short-Chain Chlorinated Paraffin Congener, 1,2,5,6,9,10-C10H16Cl6, in a Rice Seedling Hydroponic Exposure System
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 期号: 0, 页码: 1-11
作者:
Chen, Weifang
;
Hou, Xingwang
;
Mao, Xiaowei
;
Jiao, Suning
;
Wei, Linfeng
  |  
收藏
  |  
浏览/下载:145/0
  |  
提交时间:2022/11/08
POLYCHLORINATED-BIPHENYLS PCBS
HYDROXYLATED METABOLITES
ARABIDOPSIS-THALIANA
PHYTOREMEDIATION
TRANSLOCATION
TRENDS
AIR
DECHLORINATION
CONJUGATION
EXCRETION
FEK self-assembled peptide hydrogels facilitate primary hepatocytes culture and pharmacokinetics screening
期刊论文
OAI收割
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2022, 页码: 13
作者:
He, Ting
;
Qiao, Shida
;
Ma, Chen
;
Peng, Zhaoliang
;
Wu, Zhitao
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/06/15
biliary excretion index
FEFEFKFK self-assembling peptide hydrogel
metabolic enzymes
rat primary hepatocytes
sandwich culture
transporters
Understanding the excretion rates of methylmercury and inorganic mercury from human body via hair and fingernails
期刊论文
OAI收割
Journal of Environmental Sciences, 2022, 卷号: 119, 页码: 59-67
作者:
Wei Zhang
;
Fen Li
;
Lingjian Gao
;
Guangyi Sun
;
Zikang Cui
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/03/16
Mercury
Methylmercury
hair
Fingernails
Biomarker
excretion Rate
2,4,6-三溴苯酚在水稻体内生物转化过程及其 II 相代谢产物区隔化特征
学位论文
OAI收割
北京: 中国科学院生态环境研究中心, 2020
作者:
张 青
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/06/23
2,4,6-三溴苯酚,水稻幼苗和细胞,植物代谢,Ii 相代谢产物,分泌过程,区隔化,植物解毒
2,4,6-tribromophenol, Rice Plants And Cells, Plant Metabolism, Phase Ii Conjugates, Plant Excretion, Spatial Compartmentation, Plant Detoxification
Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Pan, Lu-lu
;
Yang, Yong
;
Hui, Min
;
Wang, Shuo
;
Li, Cui-yun
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/12/24
forsythin
pharmacokinetics
drug metabolism
drug excretion
sulfation
glucuronidation
organic anion transporter 3
Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 398-416
作者:
Wang, Yibing
;
Lou, Yang
;
Wang, Jiang
;
Li, Dan
;
Chen, Hui
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
SGLT2 inhibitors
Diabetes
Sugar modification
Structure-activity relationship
Urinary glucose excretion
Oral glucose tolerance
A Validated HPLC-MS/MS Assay for 14-O-[(4,6-Diaminopyrimidine-2-yl)thioacetyl] Mutilin in Biological Samples and Its Pharmacokinetic, Distribution and Excretion via Urine and Feces in Rats
期刊论文
OAI收割
MOLECULES, 2019, 卷号: 24, 期号: 4, 页码: 17
作者:
Shang, Ruofeng
;
Fu, Yunxing
;
Liu, Yu
;
Yi, Yunpeng
;
Liang, Jianping
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/11/10
DPTM
HPLC-MS
MS
pharmacokinetics
distribution
excretion