中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
上海生物化学与细胞生... [5]
昆明动物研究所 [2]
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OAI收割 [12]
内容类型
期刊论文 [12]
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2024 [2]
2021 [1]
2019 [1]
2018 [3]
2015 [3]
2014 [2]
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Biochemist... [1]
Cell Biolo... [1]
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共12条,第1-10条
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Design, Synthesis, and Bioevaluation of Transcriptional Enhanced Assocciated Domain (TEAD) PROTAC Degraders
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 5, 页码: 631-639
作者:
Li, Huajie
;
Ge, Zhiming
;
Lin, Kexin
;
He, Wei
;
Chu, Qinyu
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/06/27
Hippo pathway
TEAD
PROTAC
Selectivity
Regulation of hippo signaling mediated apoptosis by
Rauvolfia tetraphylla
in triple-negative breast cancer
期刊论文
OAI收割
MEDICAL ONCOLOGY, 2024, 卷号: 41, 期号: 5, 页码: 14
作者:
Balavaishnavi, B.
;
Kamaraj, M.
;
Nithya, T. G.
;
Santhosh, P.
;
Gokilalakshmi, S.
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/07
Anti-proliferative effect
Hippo pathway
MDA-MB-231 cells
Apoptosis
Rauvolfia tetraphylla
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:
Lu, Tian
;
Li, Yong
;
Lu, Wenchao
;
Spitters, Twgm
;
Fang, Xueyu
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/12/01
Hippo pathway
TEAD3
Covalent inhibitor
Palmitoylation inhibitor
Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:
Lu, Wenchao
;
Wang, Jun
;
Li, Yong
;
Tao, Hongru
;
Xiong, Huan
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2020/07/01
Hippo pathway
TEAD transcription factor
Covalent inhibitor
Palmitoylation inhibitor
Cyclopeptide RA-V Inhibits Organ Enlargement and Tumorigenesis Induced by YAP Activation
期刊论文
OAI收割
CANCERS, 2018, 卷号: 10, 期号: 11
作者:
Ji, Xinyan
;
Song, Lihua
;
Sheng, Li
;
Gao, Anhui
;
Zhao, Yang
  |  
收藏
  |  
浏览/下载:95/0
  |  
提交时间:2019/01/08
hippo pathway
YAP
TAZ
RA-V
cancer
organ size
protein synthesis
Targeting IRF3 as a YAP agonist therapy against gastric cancer
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL MEDICINE, 2018, 卷号: 215, 期号: 2, 页码: 699-718
作者:
Jiao, Shi
;
Guan, Jingmin
;
Chen, Min
;
Wang, Wenjia
;
Li, Chuanchuan
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/04/28
Hippo Signaling Pathway
Organ Size Control
Interferon Regulatory Factor-3
Minor Aphthous Ulceration
Cell Contact Inhibition
Tumor-suppressor
Innate Immunity
Growth-control
Intestinal Regeneration
Colorectal-cancer
PRDM4 mediates YAP-induced cell invasion by activating leukocyte-specific integrin beta 2 expression
期刊论文
OAI收割
EMBO REPORTS, 2018, 卷号: 19, 期号: 6, 页码: -
作者:
Liu, Huan
;
Dai, Xiaoming
;
Cao, Xiaolei
;
Yan, Huan
;
Ji, Xinyan
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/04/28
Yes-associated Protein
Histone Methyltransferase Complex
Hippo Signaling Pathway
Organ Size Control
Transcription Factor
Prostate-cancer
Tissue Homeostasis
Gene-expression
Growth-control
Myeloid Cells
Structural dissection of Hippo signaling
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2015, 卷号: 47, 期号: 1, 页码: 29-38
作者:
Shi, ZB
;
Jiao, S
;
Zhou, ZC
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2015/07/22
Hippo pathway
three-dimensional structure
protein-protein
DNA interaction
regulatory mechanism
The interplay between TEAD4 and KLF5 promotes breast cancer partially through inhibiting the transcription of p27(Kip1)
期刊论文
OAI收割
ONCOTARGET, 2015, 卷号: 6, 期号: 19, 页码: 17685-17697
作者:
Wang CY
;
Nie Z
;
Zhou ZM
;
Zhang HL
;
Liu R
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2015/09/01
TEAD4
KLF5
p27
hippo pathway
TNBC
Hippo pathway in mammary gland development and breast cancer
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2015, 卷号: 47, 期号: 1, 页码: 53-59
作者:
Shi PG
;
Feng J[*]
;
Chen CS[*]
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2015/02/06
Hippo pathway
YAP
TAZ
mammary gland development
breast cancer