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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [2]
长春光学精密机械与物... [1]
心理研究所 [1]
武汉物理与数学研究所 [1]
武汉植物园 [1]
采集方式
OAI收割 [6]
内容类型
期刊论文 [5]
会议论文 [1]
发表日期
2020 [1]
2019 [2]
2017 [1]
2012 [1]
2008 [1]
学科主题
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Type 2 diabetes can undermine driving performance of middle-aged male drivers through its deterioration of perceptual and cognitive functions
期刊论文
OAI收割
ACCIDENT ANALYSIS AND PREVENTION, 2020, 卷号: 134, 页码: 7
作者:
Ma, Shu
;
Zhang, Jingyu
;
Zeng, Xianzhong
;
Wu, Changxu
;
Zhao, Guozhen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/02/29
Type 2 diabetes
Non-hypoglycemia
Driving performance
Perceptual and cognitive functions
The Water Diffusion of Brain Following Hypoglycemia in Rats - A Study with Diffusion Weighted Imaging and Neuropathologic Analysis
期刊论文
OAI收割
NEUROSCIENCE, 2019, 卷号: 409, 页码: 58-68
作者:
Tong, Fang
;
Zou, Yijuan
;
Liang, Yue
;
Lei, Hao
;
Lopsong, Tenzin
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/10/14
DWI
hypoglycemia
neuropathology
water diffusion
The Water Diffusion of Brain Following Hypoglycemia in Rats - A Study with Diffusion Weighted Imaging and Neuropathologic Analysis
期刊论文
OAI收割
NEUROSCIENCE, 2019, 卷号: 409, 页码: 58-68
作者:
Tong, Fang
;
Zou, Yijuan
;
Liang, Yue
;
Lei, Hao
;
Lopsong, Tenzin
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/10/17
DWI
hypoglycemia
neuropathology
water diffusion
Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 页码: 128-152
作者:
Wang, Zhengyu
;
Shi, Xiaofan
;
Zhang, Huan
;
Yu, Liang
;
Cheng, Yanhua
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
Type 2 diabetes mellitus
Hypoglycemia
Dyslipidemia
Glucokinase activators
N-Thiazol-2-yl-benzamides
PID control of glucose concentration in subjects with type 1 diabetes based on a simplified model: An in silico trial (EI CONFERENCE)
会议论文
OAI收割
10th World Congress on Intelligent Control and Automation, WCICA 2012, July 6, 2012 - July 8, 2012, Beijing, China
作者:
Yu L.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2013/03/25
An artificial pancreas system (APS) mimics the function of a real pancreas through monitoring a diabetic's blood glucose and administering the right dose of insulin via an automatic control loop. It is hailed as a promising cure of diabetes
though this technology is still years away from commercial use due to a few technological bottlenecks. The simulation model of insulin-glucose metabolism of type 1 diabetes mellitus (T1DM) is an essential part of APS. In order to simplify the parameter identification task so that the model can be implemented electronically with ease
this paper presents a simplified model based on Routh approximation model reduction method. The results show that the approximation error between the simplified model and the original model is so small that can be neglected. Based on the simplified model
a PID controller is designed to maintain normoglycemia (90mg/dl) in subjects with T1DM. The in silico simulation results show that the glucose concentration is controlled well
the risk of hyperglycemia and hypoglycemia is reduced a lot. This suggests that the simplified model describes the insulin-glucose metabolism process accurately
and the PID control algorithm is well-suitable to guide the further development of an APS. 2012 IEEE.
Insulin-releasing activity of a series of phenylalanine derivatives
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 9, 页码: 1997-2003
作者:
Tang, Lei
;
Yu, Juanhong
;
Wu, Haoshu
;
Fan, Houxing
;
Yang, Yushe
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Insulin-releasing activity
Insulin-sensitizing activity
Hypoglycemia effect
Phenylalanine