中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
金属研究所 [2]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2019 [1]
2018 [1]
2007 [2]
2006 [4]
学科主题
Chemistry [1]
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Simultaneous determination of imrecoxib and its two active metabolites in plasma of hepatic impairment patients by liquid chromatography-tandem mass spectrometry
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2019, 卷号: 1122, 页码: 58-63
作者:
Hou, Xiangyu
;
Dai, Xiaojian
;
Yang, Yong
;
Zhang, Yifan
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Imrecoxib
Imrecoxib active metabolites
Pharmacokinetics
LC-MS/MS
Human
Moderate impairment
Effect of Fluconazole on the Pharmacokinetic Properties of Imrecoxib, a Novel NSAID: A Single-center, Open-label, Self-controlled Study in Healthy Chinese Male Volunteers
期刊论文
OAI收割
CLINICAL THERAPEUTICS, 2018, 卷号: 40, 期号: 8, 页码: 1347-1356
作者:
Zuo, Cheng-zi
;
Gong, Yi
;
Hou, Xiang-yu
;
Zhang, Yi-fan
;
Peng, Wen-xing
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/01/08
COX-2 inhibitor
drug interaction
fluconazole
imrecoxib
pharmacokinetics
NASID
Molecular docking study of the affinity of CYP2C9 and CYP2D6 for imrecoxib
期刊论文
OAI收割
JOURNAL OF THEORETICAL & COMPUTATIONAL CHEMISTRY, 2007, 卷号: 6, 期号: 3, 页码: 541-548
作者:
Yao, Yuan
;
Han, Wei-Wei
;
Zhou, Yi-Han
;
Li, Ze-Sheng
;
Li, Qiang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
cytochrome P450s
imrecoxib
molecular docking
Metabolism and excretion of imrecoxib in rat
期刊论文
OAI收割
XENOBIOTICA, 2006, 卷号: 36, 期号: 5, 页码: 441-455
作者:
Xu, H.
;
Zhang, Y.
;
Sun, Y.
;
Zhang, P.
;
Chu, F.
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
imrecoxib
metabolism
Formation of 4 '-carboxyl acid metabolite of imrecoxib by rat liver microsomes
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2006, 卷号: 27, 期号: 4, 页码: 506-512
作者:
Xu, HY
;
Zhang, P
;
Gong, AS
;
Sun, YM
;
Chu, FM
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
imrecoxib
cytochrome P450
metabolism
liver microsomes
rats
Role of rat liver cytochrome P450 3A and 2D in metabolism of imrecoxib
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2006, 卷号: 27, 期号: 3, 页码: 372-380
作者:
Xu HY
;
Xie ZY
;
Zhang P
;
Sun J
;
Chu FM
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/02/02
NONSTEROIDAL ANTIINFLAMMATORY DRUGS
COX-2 INHIBITORS
IN-VITRO
MICROSOMES
CYCLOOXYGENASE-2
OSTEOARTHRITIS
ISOENZYMES
NSAIDS
VIVO
imrecoxib
cytochrome P450
metabolism
liver microsomes
Formation of 4 '-carboxyl acid metabolite of imrecoxib by rat liver microsomes
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2006, 卷号: 27, 期号: 4, 页码: 506-512
作者:
Xu HY
;
Zhang P
;
Gong AS
;
Sun YM
;
Chu FM
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/02/26
PRIMARY CULTURES
CYCLOOXYGENASE-2
HEPATOCYTES
INDUCTION
imrecoxib
cytochrome P450
metabolism
liver microsomes
rats