中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
近代物理研究所 [1]
采集方式
OAI收割 [4]
内容类型
期刊论文 [4]
发表日期
2021 [1]
2019 [1]
2011 [1]
2002 [1]
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Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Wei, Yuan-yuan
;
Ma, Yan
;
Yao, Song-yu
;
Kong, Ling-hui
;
Liu, Xiao
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/11/04
kappa-opioid receptor agonist
4,5-expoxymorphinan
antinociception
conditioned place aversion
sedation
U50,488H
morphine
Nor-BNI
beta-FNA
How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the kappa-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 3, 页码: 1575-1584
作者:
An, Xiaoli
;
Bai, Qifeng
;
Bing, Zhitong
;
Zhou, Shuangyan
;
Shi, Danfeng
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/11/10
kappa-opioid receptor
Gaussian accelerated molecular dynamics simulation
agonist
antagonist
conformational change
Synthesis and evaluation of kappa-opioid receptor agonistic activity and antinociceptive effect of novel morphine analogues, 7 alpha-phenyl-6 alpha,14 alpha-endo-etheno-tetrahydrothebaine with substituted o-, m- and p-amino group
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2011, 卷号: 20, 期号: 8, 页码: 1364-1370
作者:
Qi, Hong
;
Li, Wei
;
Qiu, Yu
;
Cui, Yong-yao
;
Ma, Jian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
kappa-Opioid receptor
Opioid agonist
Antinociception
Enantiospecific synthesis of all four Stereoisomers of novel bicyclic arylacetamides as kappa-Opioid agonists
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2002, 卷号: 20, 期号: 10, 页码: 1073-1079
作者:
Long, YQ
;
Mou, QY
;
Qiu, DP
;
Wu, RQ
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
kappa-Opioid receptor agonist
bicyclic arylacetamide
conformational restriction
enantiospecific synthesis