中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [26]
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Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13
作者:
Li, Kun
;
Zeng, Yue
;
Xiong, Yi-da
;
Wu, Hao-chen
;
Fang, Sui
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/08/20
drug-target affinity prediction
virtual screening
contrastive learning
graph neural network
N
-methyl-
D
-aspartate (NMDA) receptors
GluN3A subunit.
Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8
作者:
Wang, Shi-hang
;
Zeng, Yue
;
Yang, Hao
;
Tian, Si-yuan
;
Zhou, Yong-qi
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/07/25
N
-methyl-
D
-aspartate receptors
GluN1/GluN3A
ligand-based virtual screening
scaffold hopping
deep learning
GeminiMol
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Wang, Ze-chen
;
Zeng, Yue
;
Sun, Jin-yuan
;
Chen, Xue-qin
;
Wu, Hao-chen
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery
Recent Developments and Future Directions in Flow Visualization: Experiments and Techniques
期刊论文
OAI收割
FLUIDS, 2025, 卷号: 10, 期号: 2
作者:
Ge, Mingming
;
Zhang, Guangjian
;
Zhang XL(张鑫磊)
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/07/21
n/a
Single-cell sequencing analysis reveals the essential role of the m6A reader YTHDF1 in retinal visual function by regulating TULP1 and DHX38 translation
期刊论文
OAI收割
ZOOLOGICAL RESEARCH, 2025, 卷号: 46, 期号: 2, 页码: 429
作者:
Zhu, Xian-Jun
;
Jiang, Xiao-Yan
;
Liu, Wen-Jing
;
Fan, Yu-Di
;
Liu, Guo
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/11/27
Epitranscriptomics
N6-methyladenosine (m6A)
Inherited retinal dystrophies (IRDs)
YTHDF1
Single-cell RNA sequencing
Photoreceptor degeneration
Application of life history theory to explain the association between childhood maltreatment and adulthood sleep problems in Chinese men with drug abuse: multiple mediating roles of emotion regulation, future-oriented coping, and anxiety
期刊论文
OAI收割
EUROPEAN JOURNAL OF PSYCHOTRAUMATOLOGY, 2024, 卷号: 15, 期号: 1, 页码: 14
作者:
Feng, Chun
;
Wu, Anise M. S.
;
Chen, You-Ping
;
Xing, Yong
;
Zhai, Rui
  |  
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2024/11/26
Evolutionary theory
childhood experience
emotion regulation
anxiety
sleep problems
Teor & iacute
experiencia infantil
regulaci & oacute
ansiedad
problemas de sue & ntilde
a evolutiva
n emocional
o
MGAT4A/Galectin9-Driven
N
-Glycosylation Aberration as a Promoting Mechanism for Poor Prognosis of Endometrial Cancer with
TP53
Mutation
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 19
作者:
Zhu, Zhen
;
Sun, Jingya
;
Xu, Weiqing
;
Zeng, Qinghe
;
Feng, Hanyi
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2024/12/11
endometrial cancer
glucose metabolism
MGAT4A
N
-glycosylation
TP53
mutation
Adsorption mechanism of Cs + and Pb 2+on the N-A-S-H surface under the different Si/Al ratio and temperature
期刊论文
OAI收割
JOURNAL OF MOLECULAR LIQUIDS, 2024, 卷号: 401, 页码: 15
作者:
Zhang, Wei
;
Lang, Lei
;
Chen, Xin
;
Huang, Kang
;
Li, Jiang-Shan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/06/27
Adsorption mechanism
Heavy metals
N-A-S-H gel
Si/Al ratio
Temperature
Learning Sequential and Structural Dependencies Between Nucleotides for RNA N6-Methyla-denosine Site Identification
期刊论文
OAI收割
IEEE/CAA Journal of Automatica Sinica, 2024, 卷号: 11, 期号: 10, 页码: 2123-2134
作者:
Guodong Li
;
Bowei Zhao
;
Xiaorui Su
;
Dongxu Li
;
Yue Yang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/09/03
Cross-domain reconstruction
cross-species prediction
N6-methyladenosine (m6A) modification site
RNA sequence
sequential and structural dependencies
Development of an inducible Cas9 nickase and PAM-free Cas12a platform for bacterial diagnostics
期刊论文
OAI收割
TALANTA, 2023, 卷号: 265, 页码: 6
作者:
Hu, Yuanzhao
;
Qiao, Yuefeng
;
Li, Xiu-Qing
;
Xiang, Zhenbo
;
Wan, Yi
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2023/12/13
Bacteria diagnostics
CRISPR-Cas9n
CRISPR-Cas12a
Strand displacement