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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [2]
南海海洋研究所 [1]
金属研究所 [1]
长春光学精密机械与物... [1]
自动化研究所 [1]
长春应用化学研究所 [1]
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OAI收割 [7]
内容类型
期刊论文 [6]
会议论文 [1]
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2022 [2]
2019 [1]
2016 [1]
2013 [1]
2010 [1]
2007 [1]
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学科主题
Chemistry [1]
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A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 11
作者:
Zeng, Yue
;
Shi, Wei
;
Dong, Qian
;
Li, Wanzhen
;
Zhang, Jianxin
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2022/08/30
Acyl Transfer
Anti-Tumor
One-Step Synthesis
Site-Specific ADCs
Thioester
One-step synthesis of site-specific antibody-drug conjugates by reprograming IgG glycoengineering with LacNAc-based substrates
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2417-2428
作者:
Shi, Wei
;
Li, Wanzhen
;
Zhang, Jianxin
;
Li, Tiehai
;
Song, Yakai
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2022/08/16
Site-specific ADCs
ENGase
LacNAc
One-step assembly
Potent in vivo efficacy
ASAF: altered spontaneous activity fingerprinting in Alzheimer's disease based on multisite fMRI
期刊论文
OAI收割
SCIENCE BULLETIN, 2019, 卷号: 64, 期号: 14, 页码: 998-1010
作者:
Li, Jiachen
;
Jin, Dan
;
Li, Ang
;
Liu, Bing
;
Song, Chengyuan
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/12/16
Brain spontaneous activity
Multisite
Biomarkers
Leave-one-site-out cross-validation
Alzheimer's disease
Site selective synthesis of cytotoxic 1,3,6-trisubstituted 3,6-diunsaturated (3Z,6Z)-2,5-diketopiperazines via a one-pot multicomponent method
期刊论文
OAI收割
TETRAHEDRON, 2016, 卷号: 72, 期号: 8, 页码: 1051-1057
作者:
Liao, Sheng-Rong
;
Du, Li-Juan
;
Qin, Xiao-Chu
;
Xu, Liang
;
Wang, Jun-Feng
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2016/12/26
2,5-Diketopiperazines
One-pot
Multicomponent
Site selectivity
Adol condensation
Acid-base bifunctional HPA nanocatalysts promoting heterogeneous transesterification and esterification reactions
期刊论文
OAI收割
catalysis science & technology, 2013, 卷号: 3, 期号: 9, 页码: 2204-2209
Zhao Q
;
Wang H
;
Zheng HW
;
Sun Z
;
Shi W
;
Wang ST
;
Wang XH
;
Jiang ZJ
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2014/04/18
MESOPOROUS MATERIALS
ONE-POT
BIODIESEL PRODUCTION
FUNCTIONAL-GROUPS
SOLID CATALYST
SILICA
SITE
HETEROPOLYMOLYBDATES
ALCOHOLS
AMINE
Efficacy and tolerability of one-site versus two-site phaco-trabeculectomy: a meta-analysis of randomized controlled clinical trials
期刊论文
OAI收割
CHINESE MEDICAL JOURNAL, 2010, 卷号: 123, 期号: 15, 页码: 2111-2115
作者:
Liu Henan
;
Chen Xiaolong
;
Li Xun
;
Nie Qingzhu
;
Zhu Ying
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/02/26
OPEN-ANGLE GLAUCOMA
INTRAOCULAR-PRESSURE
CORNEAL PHACOEMULSIFICATION
LENS IMPLANTATION
COMBINED CATARACT
PHACOTRABECULECTOMY
SURGERY
EYES
3-YEAR
1-SITE
phacotrabeculectomy
one-site
two-site
meta-analysis
Research on the support structure of the primary mirror of large-aperture telescope (EI CONFERENCE)
会议论文
OAI收割
3rd International Symposium on Advanced Optical Manufacturing and Testing Technologies, AOMATT 2007: Large Mirrors and Telescopes, July 8, 2007 - July 12, 2007, Chengdu, China
Yang W.
;
Jingxu Z.
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2013/03/25
Large-aperture telescope can be used in surveying battlefield
researching landform
searching object
real-time monitoring
imaging
detecting and identifying spatial targets and so on. A large-aperture telescope for achieving high resolution power is designed to monitor spatial target and image in real time. Real-time monitoring plays an important role in military conflicts. The orbit parameter of object
quantity
geometrical shape parameter and so on can be obtained by detect spatial target. With the development of optical technology
people require larger aperture in optics-electronic (OE) system. By increasing optical aperture
the ability of collecting light and resolution power in the system can be enhanced. But the support structure of the primary mirror of large-aperture telescope will be a very difficult problem. With the increase of primary mirror aperture
the weight of the primary mirror will become larger than before. The root mean square (rms) of the primary mirror is affected by many factors
such as deadweight
deformation of heat
environment and so on. Due to the primary mirror of telescope is an important component of telescope system. By reducing the weight of primary mirror
precision of the system is ensured. During the designing phase
one can consider the supporting project of the primary mirror synthetically and analyze it roundly according to technical requirement of optical system and the effect factors. The final structural design can be reasonable. In an astronomical telescope
the surface of reflector is an important part for collecting dark radiation of celestial bodies. Its surface shape will have an effect on collecting efficiency of telescope radiant energy directly. So the rms must be very high. Optical system of large aperture
small wavelength and small focus can receive maximal light intensity. For ground-based optical astronomical telescope
the design proposed in the paper can satisfy the requirement of the possible minimum atmosphere seeing at astronomical observatory site and exert the use efficiency of the telescope adequately. So the accuracy of the traditional surface of reflector can assure that 90% of all the light energy can be focused on within the angle diameter range of the minimum atmosphere seeing
then 100% of light energy should be focused on the angle diameter range of minimum atmosphere seeing. Because the rms of mirror is very high
precise surface machining and accurate the support of mirror are very important tasks during designing and manufacturing the telescope. In the paper
various support techniques of a large-aperture telescope primary mirror are discussed and a 3.5 meter telescope system at the Starfire Optical Range (SOR) overviewed simply
which was operated by the Directed Energy Directorate of the Air Force Research Laboratory
Kirtland AFB
NM
USA from the ground-based O-E system for the observations of spatial target. We also analyze Theoretical elastic deformation of the Steward Observatory 2.3 meter mirror is analyzed.