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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2025 [1]
2021 [1]
2009 [2]
2008 [1]
2002 [1]
1996 [1]
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Dezocine Exerts Analgesic Effects in Chronic Pain by Activation of κ- and μ-Opioid Receptors and Inhibition of Norepinephrine and Serotonin Reuptake
期刊论文
OAI收割
PAIN RESEARCH & MANAGEMENT, 2025, 卷号: 2025, 期号: 1, 页码: 9
作者:
Liu, Zihan
;
Liu, Anan
;
Chen, Jing
;
Chai, Jing-Rui
;
Liu, Panwen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/05/27
analgesic
chronic pain
dezocine
norepinephrine reuptake
opioid receptor
serotonin reuptake
Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective mu Opioid Receptor Agonists
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 2, 页码: 285-299
作者:
Huang, Huoming
;
Li, Xinwei
;
Guo, Wei
;
Zhu, Chen
;
Qian, Yuanyuan
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
pain
opioid analgesic
SAR
selective MOR agonist
molecular dynamics simulations
Synthesis and biological activities of N-indolalkyl piperidine derivatives and their analogues
期刊论文
OAI收割
Chinese Journal of Medicinal Chemistry, 2009, 卷号: 19, 期号: 3, 页码: 161-169
作者:
WANG Guan
;
ZHANG Gui-sen
;
GUO Lin
;
YU Lei-ping
;
LI Jian-qi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
N-indolalkyl piperidine derivatives
synthesis
5-HT reuptake inhibitors
5-HT_(2A) recepetor
non-opioid analgesic activity
Design,synthesis and antalgic activities of aralkyl-ketone-4-piperidol derivatives
期刊论文
OAI收割
Acta Pharmaceutica Sinica, 2009, 卷号: 44, 期号: 4, 页码: 371-378
作者:
WANG Guan
;
ZHANG Gui-sen
;
GUO Lin
;
CHEN Jie
;
LI Jian-qi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
aralkyl-ketone-4-piperidol derivatives
synthesis
non-opioid analgesic
Synthesis and central none-opioid analgesic activity of SIPI5047
期刊论文
OAI收割
Acta Pharmaceutica Sinica, 2008, 卷号: 43, 期号: 6, 页码: 611-618
作者:
LI Jianqi
;
HUANG Liying
;
CHEN Xinjian
;
WENG Zhijie
;
ZHANG Chunnian
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
SIPI5047
SIPI5047
synthesis
central none-opioid analgesic agent
Synthesis of hexahydro-1H-1,4-diazepine analogues carrying the segment of (1-arylacetamide-2-tertiary amide) ethane and their analgesic effects
期刊论文
OAI收割
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2002, 卷号: 23, 期号: 4, 页码: 585-590
作者:
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
selective kappa-opioid receptor agonists
analgesic effect
hexahydro-1H-1
4-diazepine analogues
(1-arylacetamide-2-tertiary amide) ethane structure
Molecular modeling of mu opioid receptor and its interaction with ohmefentanyl
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 1996, 卷号: 17, 期号: 2, 页码: 156-160
作者:
Tang, Y
;
Chen, KX
;
Jiang, HL
;
Wang, ZX
;
Ji, RY
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
molecular models
mu opioid receptor
ohmefentanyl
analgesic
3D structure-activity relationship