中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [68]
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期刊论文 [297]
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Improving Rice Grain Quality Through Ecotype Breeding for Enhancing Food and Nutritional Security in Asia-Pacific Region
期刊论文
OAI收割
RICE, 2024, 卷号: 17, 期号: 1, 页码: 21
作者:
Alam, Mufid
;
Lou, Guangming
;
Abbas, Waseem
;
Osti, Rajani
;
Ahmad, Aqeel
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/10/08
Food security
Nutritional security
Functionality
Protein
Flavor
Structure-functional relationship
Interaction-Based Inductive Bias in Graph Neural Networks: Enhancing Protein-Ligand Binding Affinity Predictions From 3D Structures
期刊论文
OAI收割
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2024, 卷号: 46, 期号: 12, 页码: 8191-8208
作者:
Yang, Ziduo
;
Zhong, Weihe
;
Lv, Qiujie
;
Dong, Tiejun
;
Chen, Guanxing
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/01/14
Proteins
Programmable logic arrays
Three-dimensional displays
Predictive models
Graph neural networks
Data models
Convolution
Protein-ligand binding affinity
graph neural networks
inductive bias
drug-target interaction
structure-based virtual screening
Synchrotron Radiation: A Key Tool for Drug Discovery
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 114, 页码: 10
作者:
Li, Fengcheng
;
Liu, Runze
;
Li, Wenjun
;
Xie, Mingyuan
;
Qin, Song
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/12/06
Synchrotron radiation
Drug discovery
Protein crystals
Structure determination
Ligand screening
Synchrotron Radiation: A Key Tool for Drug Discovery
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 114, 页码: 10
作者:
Li, Fengcheng
;
Liu, Runze
;
Li, Wenjun
;
Xie, Mingyuan
;
Qin, Song
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/06
Synchrotron radiation
Drug discovery
Protein crystals
Structure determination
Ligand screening
GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states
期刊论文
OAI收割
BMC BIOINFORMATICS, 2024, 卷号: 25, 期号: 1, 页码: 16
作者:
Liu, Fan
;
Zhou, Han
;
Li, Xiaonong
;
Zhou, Liangliang
;
Yu, Chungong
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/12/06
G-protein coupled receptor
State-specific structure
Binding site
Key residue
Database
Optimizing dietary habits for climate benefits in China: Greenhouse gas emissions and sustainable substitution strategies
期刊论文
OAI收割
SUSTAINABLE PRODUCTION AND CONSUMPTION, 2024, 卷号: 51, 页码: 292-302
作者:
Du, Yiqiong
;
Zhao, Zhe
;
Zhang, Fan
;
Du, Ziqiang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/11/19
Dietary structure
Protein gap
Food substitution scenario
Greenhouse gas emissions
Emissions reduction potential
FuncPhos-STR: An integrated deep neural network for functional phosphosite prediction based on AlphaFold protein structure and dynamics
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 266, 页码: 11
作者:
Zhang, Guangyu
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/06/27
Functional phosphosite
Deep learning
AlphaFold protein structure
Dynamics
Protein protein interaction
Single-sequence protein structure prediction by integrating protein language models
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 13, 页码: 7
作者:
Jing, Xiaoyang
;
Wu, Fandi
;
Luo, Xiao
;
Xu, Jinbo
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/20
protein structure prediction
protein language model
single-sequence protein structure rediction
antibody structure prediction
single mutation effect
Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP)
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 2, 页码: 270-279
作者:
Zhou, Chenmao
;
Hao, Xinyue
;
Chen, Zhengyang
;
Zhang, Runze
;
Zhou, Qian
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/03/13
Speckle-type POZ protein (SPOP)
SPOP inhibitors
Clear cell renal cell carcinoma (ccRCC)
Structure-activityrelationship (SAR)
Structural framework for the understanding spectroscopic and functional signatures of the cyanobacterial Orange Carotenoid Protein families
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 254, 页码: 20
作者:
Sluchanko, Nikolai N.
;
Maksimov, Eugene G.
;
Slonimskiy, Yury B.
;
Varfolomeeva, Larisa A.
;
Bukhanko, Antonina Y.
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/01/26
Photoprotection
Phycobilisome fluorescence quenching
Crystal structure
Protein-protein interaction
Absorption spectroscopy
Photoactivity
SEC-MALS