中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
福建物质结构研究所 [1]
采集方式
OAI收割 [4]
内容类型
期刊论文 [4]
发表日期
2021 [1]
2020 [1]
2017 [1]
2007 [1]
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Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 31, 页码: 4
作者:
Xiang, Hao-Yue
;
Chen, Jian-Yang
;
Huan, Xia-Juan
;
Chen, Yi
;
Gao, Zhao-bing
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/05/24
Antiproliferative
Cancer
PARP inhibitors
Pyrrolo[12-b]pyridazine
Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14
作者:
Chen, Yun
;
Bai, Gang
;
Ning, Yi
;
Cai, Shi
;
Zhang, Tao
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2020/07/01
lnterleukin-1 receptor associated kinase 4
Imidazol1,2-6]pyridazine
Diffuse large B-cell lymphoma
Drug design
Antitumor agents
Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 598-611
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Xie, Xiao-Yu
;
Pan, You-Lu
;
Li, Gang-Jian
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Pyridazine-3-carboxamides
CB2 agonist
Structure-activity relationships
Molecular docking
logP
Metal-coordination-directed assembly of binuclear trigonal prisms and three-dimensional hydrogen-bonded networks
期刊论文
OAI收割
Inorganic Chemistry, 2007, 卷号: 46, 期号: 14, 页码: 5471-5473
W. W. Sun
;
A. L. Cheng
;
Q. X. Jia
;
E. Q. Gao
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2013/04/01
crystal-structures
stacking interactions
molecular networks
pi
interactions
complexes
design
anion
construction
pyridazine
behavior