中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
上海神经科学研究所 [1]
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OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2023 [1]
2019 [1]
2018 [1]
2009 [1]
2008 [1]
学科主题
Chemistry [1]
Neuroscien... [1]
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Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Discovery of Novel Retigabine Derivatives as Potent KCNQ4 and KCNQ5 Channel Agonists with Improved Specificity
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 1, 页码: 27-33
作者:
Wang, Lei
;
Qiao, Guan-Hua
;
Hu, Hai-Ning
;
Gao, Zhao-Bing
;
Nan, Fa-Jun
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
KCNQ channel
retigabine
subtype selectivity
agonist
Computational insights into the subtype selectivity and "message-address-efficacy" mechanisms of opioid receptors through JDTic binding and unbinding
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 3, 页码: 482-491
作者:
Cheng, Jian-xin
;
Cheng, Tao
;
Li, Wei-hua
;
Liu, Gui-xia
;
Zhu, Wei-liang
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
G-protein-coupled receptors
opioid receptors
subtype selectivity
molecular dynamics
"message-address-efficacy" hypothesis
JDTic
Fluoxetine inhibition of glycine receptor activity in rat hippocampal neurons
期刊论文
OAI收割
BRAIN RESEARCH, 2008, 卷号: 1239, 期号: pt 1, 页码: 77-84
Ye, Zeng-You
;
Lu, Yun-Gang
;
Sun, Hao
;
Cheng, Xin-Ping
;
Xu, Tian-Le(徐天乐)
;
Zhou, Jiang-Ning
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2012/07/23
Antidepressant
Fluoxetine-associated seizure
Whole-cell patch-clamp
Hippocampus
Competitive inhibition
Subtype-selectivity
DORSAL-HORN NEURONS
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