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	Target Identification and Mechanistic Characterization of Indole Terpenoid Mimics: Proper Spindle Microtubule Assembly Is Essential for Cdh1-Mediated Proteolysis of CENP-A 期刊论文 OAI收割 ADVANCED SCIENCE, 2024, 页码: 14 作者: Peng, Yan; Zhang, Yumeng; Fang, Ruan; Jiang, Hao; Lan, Gongcai \| 收藏 \| 浏览/下载：28/0 \| 提交时间：2024/07/12 Cdh1 CENP-A regulation colchicine-binding site inhibitor indole terpenoid target identification
	D3Targets-2019-nCoV: a webserver for predicting drug targets and for multi-target and multi-site based virtual screening against COVID-19 期刊论文 OAI收割 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 7, 页码: 1239-1248 作者: Shi, Yulong; Zhang, Xinben; Mu, Kaijie; Peng, Cheng; Zhu, Zhengdan \| 收藏 \| 浏览/下载：43/0 \| 提交时间：2020/12/24 COVID-19 SARS-CoV-2 Target prediction Multi-conformation Multi-site Docking D3Targets-2019-nCoV
	Proteome-wide prediction of targets for aspirin: new insight into the molecular mechanism of aspirin 期刊论文 OAI收割 PEERJ, 2016, 卷号: 4, 期号: X, 页码: e1791 作者: Dai SX; Li WX; Li GH[]; Huang JF[] 收藏 \| 浏览/下载：20/0 \| 提交时间：2016/03/21 Aspirin Binding site Cancer Cardiovascular disease Molecular docking Target
	Pocket-Based Drug Design: Exploring Pocket Space 期刊论文 OAI收割 aaps journal, 2013, 卷号: 15, 期号: 1, 页码: 228-241 Zheng XL; Gan LF; Wang EK; Wang J 收藏 \| 浏览/下载：31/0 \| 提交时间：2014/04/18 PROTEIN-LIGAND-BINDING SMALL-MOLECULE BINDING STRUCTURAL BASIS TARGET FLEXIBILITY TRANSIENT POCKETS SITE PREDICTION NORMAL-MODES RAS PROTEIN IN-SILICO DRUGGABILITY
	Automatch: Target-binding protein design and enzyme design by automatic pinpointing potential active sites in available protein scaffolds 期刊论文 OAI收割 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2012, 卷号: 80, 期号: 4, 页码: 1078-1094 作者: Zhang, Changsheng; Lai, Luhua \| 收藏 \| 浏览/下载：20/0 \| 提交时间：2019/04/09 Active Sites Matching Enzyme Design Target-binding Protein Design Backbone Flexibility Active Site Recapitulation
	CALIBRATION OF VISIBLE AND NEAR-INFRARED CHANNELS OF THE FY1C USING TIME-SERIES OBSERVATION BASED ON PSEUDO-INVARIANT TARGET SITES IN CHINA 会议论文 OAI收割 2009 Ieee International Geoscience and Remote Sensing Symposium, Vols 1-5, New York Gao, Hailiang; Gu, Xingfa; Yu, Tao; Hu, Xiuqing; Li, Xiaoying; Gong, Hui; Li, Jiaguo 收藏 \| 浏览/下载：14/0 \| 提交时间：2014/12/07 Time-series calibration vicarious calibration FY1C Pseudo-invariance target site Dunhuang test site
	Research on the support structure of the primary mirror of large-aperture telescope (EI CONFERENCE) 会议论文 OAI收割 3rd International Symposium on Advanced Optical Manufacturing and Testing Technologies, AOMATT 2007: Large Mirrors and Telescopes, July 8, 2007 - July 12, 2007, Chengdu, China Yang W.; Jingxu Z. 收藏 \| 浏览/下载：27/0 \| 提交时间：2013/03/25 Large-aperture telescope can be used in surveying battlefield researching landform searching object real-time monitoring imaging detecting and identifying spatial targets and so on. A large-aperture telescope for achieving high resolution power is designed to monitor spatial target and image in real time. Real-time monitoring plays an important role in military conflicts. The orbit parameter of object quantity geometrical shape parameter and so on can be obtained by detect spatial target. With the development of optical technology people require larger aperture in optics-electronic (OE) system. By increasing optical aperture the ability of collecting light and resolution power in the system can be enhanced. But the support structure of the primary mirror of large-aperture telescope will be a very difficult problem. With the increase of primary mirror aperture the weight of the primary mirror will become larger than before. The root mean square (rms) of the primary mirror is affected by many factors such as deadweight deformation of heat environment and so on. Due to the primary mirror of telescope is an important component of telescope system. By reducing the weight of primary mirror precision of the system is ensured. During the designing phase one can consider the supporting project of the primary mirror synthetically and analyze it roundly according to technical requirement of optical system and the effect factors. The final structural design can be reasonable. In an astronomical telescope the surface of reflector is an important part for collecting dark radiation of celestial bodies. Its surface shape will have an effect on collecting efficiency of telescope radiant energy directly. So the rms must be very high. Optical system of large aperture small wavelength and small focus can receive maximal light intensity. For ground-based optical astronomical telescope the design proposed in the paper can satisfy the requirement of the possible minimum atmosphere seeing at astronomical observatory site and exert the use efficiency of the telescope adequately. So the accuracy of the traditional surface of reflector can assure that 90% of all the light energy can be focused on within the angle diameter range of the minimum atmosphere seeing then 100% of light energy should be focused on the angle diameter range of minimum atmosphere seeing. Because the rms of mirror is very high precise surface machining and accurate the support of mirror are very important tasks during designing and manufacturing the telescope. In the paper various support techniques of a large-aperture telescope primary mirror are discussed and a 3.5 meter telescope system at the Starfire Optical Range (SOR) overviewed simply which was operated by the Directed Energy Directorate of the Air Force Research Laboratory Kirtland AFB NM USA from the ground-based O-E system for the observations of spatial target. We also analyze Theoretical elastic deformation of the Steward Observatory 2.3 meter mirror is analyzed.
	Fast screening target sites for RNA interference using a cell-free system 期刊论文 OAI收割 BIOTECHNOLOGY LETTERS, 2005, 卷号: 27, 期号: 9, 页码: 619-621 作者: Huang, M; Jia, FJ; Li, CY; Li, YP; Guo, LH 收藏 \| 浏览/下载：16/0 \| 提交时间：2015/07/22 cell-free system RNA interference target site screening