中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [238]
采集方式
OAI收割 [238]
内容类型
期刊论文 [235]
会议论文 [3]
发表日期
2024 [9]
2023 [14]
2022 [24]
2021 [20]
2020 [28]
2019 [16]
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浏览/检索结果:
共238条,第1-10条
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专题:上海药物研究所
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Structurally diverse terpenoids and their DRAK2 inhibitory activities: A follow-up study on the vulnerable conifer Pseudotsuga forrestii
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1305, 页码: 13
作者:
Zhou, Peng-Jun
;
Huang, Ting
;
Ma, Guang-Lei
;
Zhao, Ze-Yu
;
Jiang, Zhe-Lu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/05/07
Pseudotsuga forrestii
Rare and endangered plants (REPs)
Triterpene-monoterpene hybrids
GLMDs
DRAK2 inhibition
Molecular docking
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis
期刊论文
OAI收割
FRONTIERS IN PLANT SCIENCE, 2024, 卷号: 15, 页码: 9
作者:
Chen, Fang-Yan
;
Mu, Qiu-Yan
;
Xu, Bing-Yi
;
Lei, Yu-Chen
;
Liu, Hui-Ying
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
artemisinin
Asteraceae sesquiterpene lactone
cytochrome P450 monooxygenases
amorpha-4
11-diene oxidase
germacrene A oxidase
molecular evolution
loss-of-function event
Characterization of diverse lysine acylations in
Bacillus thuringiensis
: Substrate profiling and functional exploration
期刊论文
OAI收割
PROTEOMICS, 2024, 页码: 13
作者:
Liu, Tianxian
;
Zhang, Mingya
;
Fan, Yameng
;
Zhao, Lei
;
Huang, Dan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Bacillus thuringiensis
conservative analysis in various species
lysine acylation
regulatory mechanism
substrate characterization
Formyl phloroglucinol meroterpenoids from the leaves of
Eucalyptus
globulus
subsp.
maidenii
and their ATP-citrate lyase inhibitory activities
期刊论文
OAI收割
FITOTERAPIA, 2024, 卷号: 173, 页码: 6
作者:
Hu, Zhu
;
Liu, Yi-Nan
;
Yu, Mei-Hua
;
Hou, Ai -Jun
;
Li, Jing-Ya
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/03/13
Eucalyptus globulus subsp. maidenii
Meroterpenoids
ATP-citrate lyase
Discovery of Pyrido[2,3-
d
]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3986-4006
作者:
Sun, Yaoliang
;
Chen, Manman
;
Han, Yuyan
;
Li, Weiqiang
;
Ma, Xiaoyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
7-Dehydrocholesterol dictates ferroptosis sensitivity
期刊论文
OAI收割
NATURE, 2024, 卷号: 626, 期号: 7998, 页码: 29
作者:
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
Safety, pharmacokinetics, and food effect of sudapyridine (WX-081), a novel anti-tuberculosis candidate in healthy Chinese subjects
期刊论文
OAI收割
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2024, 卷号: 17, 期号: 2, 页码: 10
作者:
Yu, Chengyin
;
Qian, Hongjie
;
Wu, Qingqing
;
Zou, Yang
;
Ding, Qicheng
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/06
Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 3
作者:
Yu, Lei
;
Zhao, Pengcheng
;
Sun, Yaoliang
;
Zheng, Zening
;
Du, Wenhao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/01/26