中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
采集方式
OAI收割 [18]
内容类型
期刊论文 [18]
发表日期
2019 [18]
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共18条,第1-10条
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发表日期:2019
专题:上海药物研究所
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Sinuhirtins A and B, two uncommon norhumulene-type terpenoids from the South China Sea soft coral Sinularia hirta
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 51, 页码: 4
作者:
Lu, Si-Qi
;
Li, Xu-Wen
;
Li, Song-Wei
;
Cui, Zan
;
Guo, Yue-Wei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Soft coral
Sinularia hrita
Norhumulene
Absolute configuration
Tyrosine Kinase 2 (TYK2) Allosteric Inhibitors To Treat Autoimmune Diseases
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 20, 页码: 8951-8952
作者:
Chang, Yu
;
Xu, Shilin
;
Ding, Ke
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
Vinylethylene Carbonates as alpha,beta-Unsaturated Aldehyde Surrogates for Regioselective [3+3] Cycloaddition
期刊论文
OAI收割
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 17, 页码: 6674-6678
作者:
Xu, Yi
;
Chen, Lu
;
Yang, Yu-wen
;
Zhang, Zhiqiang
;
Yang, Weibo
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
作者:
Wang, Yulan
;
Dai, Yang
;
Wu, Xiaowei
;
Li, Fei
;
Liu, Bo
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Disulfide-Containing Detergents (DCDs) for the Structural Biology of Membrane Proteins
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2019, 页码: 7
作者:
Xue, Dongxiang
;
Xu, Tiandan
;
Wang, Huixia
;
Wu, Meng
;
Yuan, Ya
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
detergents
disulfides
membrane proteins
micelle size
NMR spectroscopy
Highly diverse cembranoids from the South China Sea soft coral Sinularia scabra as a new class of potential immunosuppressive agents
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3469-3476
作者:
Yang, Min
;
Li, Heng
;
Zhang, Quan
;
Wu, Qi-Hao
;
Li, Geng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Marine natural products
Cembranoids
Soft coral
Sinularia scabra
Immunosuppressive activity
Structure-activity relationship
Klyflaccilides A and B, Diterpenoids with 6/5/8/3 Fused Tetracyclic Carbon Skeleton from the Hainan Soft Coral Klyxum flaccidum
期刊论文
OAI收割
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 14, 页码: 5660-5664
作者:
Li, Geng
;
Li, Heng
;
Tang, Wei
;
Guo, Yue-Wei
;
Li, Xu-Wen
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-kappa B Ligand (RANKL)-Receptor Activator of Nuclear Factor-kappa B (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5370-5381
作者:
Jiang, Min
;
Peng, Lei
;
Yang, Kai
;
Wang, Tianqi
;
Yan, Xueming
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Identification of a New alpha-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 6, 页码: 2683-2691
作者:
Xu, Mingming
;
Loa-Kum-Cheung, Wendy
;
Zhang, Haiyan
;
Quinn, Ronald J.
;
Mellick, George D.
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
aggregation
mass spectrometry
screening
inhibitor