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浏览/检索结果: 共78条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 页码: 12 作者:  Zhou, Jiashen;  Zhang, Lin;  Wang, Yiran;  Song, Wenyan;  Huang, Yuzhou   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/12/08 Acyl-ACP Reductases  Allosteric Regulation  Biosynthesis  Enantioselective Reduction  Enzyme Catalysis   Elastic network models and molecular dynamic simulations reveal the molecular basis of allosteric regulation in ubiquitin-specific protease 7 (USP7) 期刊论文  OAI收割 COMPUTERS IN BIOLOGY AND MEDICINE, 2023, 卷号: 162, 页码: 10 作者:  Xu, Jing;  Wang, Yiran;  Zhang, Jiali;  Abdelmoneim, Amr Abbas;  Liang, Zhongjie   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/10/17 USP7  Allosteric regulation  Elastic network models  Molecular dynamics simulations   The ketone body acetoacetate activates human neutrophils through FFAR2 期刊论文  OAI收割 JOURNAL OF LEUKOCYTE BIOLOGY, 2023, 卷号: 113, 期号: 6, 页码: 577-587 作者:  Martensson, Jonas;  Bjorkman, Lena;  Lind, Simon;  Viklund, Moa Bjerhem;  Zhang, Linjie   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 acetoacetate  FFAR2  G-protein coupled receptor  ketone body  neutrophil   A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region 期刊论文  OAI收割 JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942 作者:  Jiang, Hao;  Zu, Shijia;  Lu, Yu;  Sun, Zhongya;  Adeerjiang, Akejiang   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 Small GTPases  Crystal structures of RhoA  Dynamics of switch II  Molecular dynamics simulations  Allosteric pocket   Parthenolide reveals an allosteric mode to inhibit the deISGylation activity of SARS-CoV-2 papain-like protease 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2022, 卷号: 54, 期号: 8, 页码: 1133-1139 作者:  Zou, Zhihui;  Shan, Huizhuang;  Sun, Demeng;  Xia, Li;  Shi, Yulong   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/11/11 COVID-19  SARS-CoV-2  PLpro  Parthenolide  deISGylation   Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125 作者:  Zhang, Huimin;  He, Jixiao;  Hu, Guang;  Zhu, Fei;  Jiang, Hao   |  收藏  |  浏览/下载：55/0  |  提交时间：2022/01/04 D3DistalMutation: a Database to Explore the Effect of Distal Mutations on Enzyme Activity 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2021, 卷号: 61, 期号: 5, 页码: 2499-2508 作者:  Wang, Xiaoyu;  Zhang, Xinben;  Peng, Cheng;  Shi, Yulong;  Li, Huiyu   |  收藏  |  浏览/下载：30/0  |  提交时间：2021/08/17 Allosteric Regulation of Hsp90 alpha's Activity by Small Molecules Targeting the Middle Domain of the Chaperone 期刊论文  OAI收割 ISCIENCE, 2020, 卷号: 23, 期号: 2, 页码: 46 作者:  Zhou, Chen;  Zhang, Chi;  Zhu, Hongwen;  Liu, Zhijun;  Su, Haixia   |  收藏  |  浏览/下载：69/0  |  提交时间：2020/07/01 A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer 期刊论文  OAI收割 CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+ 作者:  Huang, Ke;  Liang, Qian;  Zhou, Ye;  Jiang, Lu-lu;  Gu, Wei-ming   |  收藏  |  浏览/下载：81/0  |  提交时间：2020/07/01 3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586 作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang   |  收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01 JAK/STAT  3-deoxy-2 beta,16-dihydroxynagilactone E  tyrosine kinase inhibitor  allosteric inhibitor  cancer