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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共143条，第1-10条 帮助

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A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression 期刊论文  OAI收割
ANTIVIRAL RESEARCH, 2024, 卷号: 221, 页码: 14
作者:  Yang, Li;  Gong, Ying;  Liu, Feifei;  Chen, Wuhong;  Wang, Xinran
  |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/19
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan
  |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11
A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10
作者:  Zhang, Yumin;  Sun, Yuan;  Xie, Yuanchao;  Shang, Weijuan;  Wang, Zhen
  |  收藏  |  浏览/下载：5/0  |  提交时间：2023/12/08
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors 期刊论文  OAI收割
PROTEIN & CELL, 2023, 卷号: 14, 期号: 1, 页码: 17-27
作者:  Zang, Yi;  Su, Mingbo;  Wang, Qingxing;  Cheng, Xi;  Zhang, Wenru
  |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27
Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 11
作者:  Wang, Ruyu;  Zhai, Guanglei;  Zhu, Guanghao;  Wang, Mengge;  Gong, Xiaoyi
  |  收藏  |  浏览/下载：13/0  |  提交时间：2023/04/10
Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540
作者:  Xie, Xiong;  Zheng, Yu-Gui;  Chen, Huan;  Li, Jian;  Luo, Rong-Hua
  |  收藏  |  浏览/下载：26/0  |  提交时间：2023/04/10
In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2 期刊论文  OAI收割
ANTIVIRAL RESEARCH, 2022, 卷号: 208, 页码: 10
作者:  Shang, Weijuan;  Dai, Wenhao;  Yao, Cheng;  Xu, Ling;  Tao, Xiangming
  |  收藏  |  浏览/下载：15/0  |  提交时间：2023/04/10
Structure-based design of a novel inhibitor of the ZIKA virus NS2B/ NS3 protease 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7
作者:  Xiong, Yanchao;  Cheng, Fei;  Zhang, Junyi;  Su, Haixia;  Hu, Hangchen
  |  收藏  |  浏览/下载：24/0  |  提交时间：2022/11/11
Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold 期刊论文  OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2022, 卷号: 298, 期号: 8, 页码: 13
作者:  Cheong, Ezekiel Ze Ken;  Quek, Jun Ping;  Xin, Liu;  Li, Chaoqiang;  Chan, Jing Yi
  |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10
Development and validation of an LC-MS/MS method for simultaneous determination of remdesivir and its hydrolyzed metabolite and nucleoside, and its application in a pharmacokinetic study of normal and diabetic nephropathy mice 期刊论文  OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2022, 页码: 10
作者:  Yuan, Meng;  Hu, Wenjuan;  Feng, Yingying;  Tong, Yue;  Wang, Xin
  |  收藏  |  浏览/下载：29/0  |  提交时间：2022/06/15