机构

• 上海药物研究所 [19]
• 合肥物质科学研究院 [4]
• 中国科学院大学 [2]
• 大连化学物理研究所 [1]
• 昆明植物研究所 [1]
• 自动化研究所 [1]
• 更多

采集方式

• OAI收割 [29]
• iSwitch采集 [2]

内容类型

• 期刊论文 [31]

发表日期

• 2024 [1]
• 2023 [3]
• 2022 [5]
• 2021 [4]
• 2020 [2]
• 2019 [2]
• 更多

学科主题

• Oncology [1]
• Science & ... [1]
• 物理化学 [1]

筛选

浏览/检索结果: 共31条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16 作者:  Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/25 Inhibitor  Cancer  Threonine tyrosine kinase (TTK)  Covalent   Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18 作者:  Zhang, Junjie;  Li, Yan;  Tang, Haotian;  Zhou, Qianqian;  Tong, Linjiang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Cancer immunotherapy  HPK1  Structure -based design  HPK1 inhibitor   Aurora A kinase inhibition compromises its antitumor efficacy by elevating PD-L1 expression 期刊论文  OAI收割 JOURNAL OF CLINICAL INVESTIGATION, 2023, 卷号: 133, 期号: 9, 页码: 12 作者:  Wang, Xiaobo;  Huang, Jing   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/17 Lenvatinib- and vadimezan-loaded synthetic high-density lipoprotein for combinational immunochemotherapy of metastatic triple-negative breast cancer 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 9, 页码: 3726-3738 作者:  Zheng, Chao;  Zhang, Wen;  Wang, Jinming;  Zhai, Yihui;  Xiong, Fengqin   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/12/13 KEY WORDS High-density lipoprotein  Immunotherapy  Combination therapy  Metastasis  Triple-negative breast cancer  Lenvatinib  Vadimezan  Immune checkpoint blockade   Systemic Therapy for Hepatocellular Carcinoma: Chinese Consensus-Based Interdisciplinary Expert Statements 期刊论文  OAI收割 LIVER CANCER, 2022, 卷号: 11 作者:  Sun, Yongkun;  Zhang, Wen;  Bi, Xinyu;  Yang, Zhengqiang;  Tang, Yu   |  收藏  |  浏览/下载：38/0  |  提交时间：2022/12/23 Chinese interdisciplinary experts  Hepatocellular carcinoma  Molecular targeted therapy  Consensus   Efficacy and safety of anlotinib with and without EGFR-TKIs or immunotherapy in the treatment of elder patients with non-small-cell lung cancer: a retrospective study 期刊论文  OAI收割 BMC PULMONARY MEDICINE, 2022, 卷号: 22 作者:  Wang, Wenxian;  Shao, Lan;  Xu, Yibing;  Song, Zhengbo;  Lou, Guangyuan   |  收藏  |  浏览/下载：22/0  |  提交时间：2022/12/23 Non-small cell lung cancer  Prognosis  Angiogenesis  Tyrosine kinase inhibitors   Treatment outcomes and prognosis of patients with primary and acquired BRAF-mutated non-small cell lung cancer: A multicenter retrospective study 期刊论文  OAI收割 GENES CHROMOSOMES & CANCER, 2022 作者:  Wang, Wenxian;  Gu, Xiaodong;  Si, Jinfei;  Pu, Xingxiang;  Wang, Liping   |  收藏  |  浏览/下载：71/0  |  提交时间：2022/05/16 BRAF mutation  immune checkpoint inhibitors  non-small cell lung cancer  PD-L1  targeted therapy   Peptidic microarchitecture-trapped tumor vaccine combined with immune checkpoint inhibitor or PI3K gamma inhibitor can enhance immunogenicity and eradicate tumors 期刊论文  OAI收割 JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 2, 页码: 13 作者:  Du, Yang;  Liu, Ye;  Wang, Di;  Bai, Hua;  Wang, Zhijie   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/06/06 immunotherapy  immunogenicity  vaccine  tumor microenvironment  lymphocytes  tumor infiltrating  macrophages   Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090 作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/01/04