机构

• 上海药物研究所 [23]

采集方式

• OAI收割 [23]

内容类型

• 期刊论文 [19]
• 会议论文 [3]
• 学位论文 [1]

发表日期

• 2024 [1]
• 2023 [1]
• 2021 [1]
• 2020 [1]
• 2019 [4]
• 2018 [1]
• 更多

学科主题

• Biochemist... [1]
• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Reversible SAHH inhibitor ameliorates MIA-induced osteoarthritis of rats through suppressing MEK/ERK pathway 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2024, 卷号: 170, 页码: 6 作者:  Fan, Shu-Hui;  Chang, Yuan;  Xiong, Xiao-Yu;  Xiang, Mai;  Yuan, Wen-Long   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/27 DZ2002  Osteoarthritis  Osteoclast  Bone resorption   DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14 作者:  Wu, Chun-mei;  Mao, Jia-wen;  Zhu, Jin-zhi;  Xie, Can-can;  Yao, Jia-ying   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 dry eye disease  DZ2002  corneal angiogenesis  immunomodulatory function  NF-kappa B  ophthalmic therapy   DZ2002 alleviates psoriasis-like skin lesions via differentially regulating methylation of GATA3 and LCN2 promoters 期刊论文  OAI收割 INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 91, 页码: 12 作者:  Chen, Li;  Lin, Zemin;  Liu, Yuting;  Cao, Shiqi;  Huang, Yueteng   |  收藏  |  浏览/下载：30/0  |  提交时间：2021/05/24 DZ2002  Psoriasis  DNA methylation  Keratinocyte  Inflammatory infiltration   dz2002抑制角质细胞分泌趋化因子改善豚鼠银屑病样皮损 期刊论文  OAI收割 中国药理学通报, 2020, 卷号: 36, 期号: 4, 页码: 501 作者:  李迁;  祁青;  杨晓倩;  杨芳明;  林泽民   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 DZ2002  psoriasis  guinea pig model of psoriasis  chemokine  cell infiltration  HaCaT  DZ2002  银屑病  豚鼠模型  趋化因子  细胞浸润  HaCaT   DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models 期刊论文  OAI收割 ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15 作者:  Zhang, Zongwang;  Wu, Yanwei;  Wu, Bing;  Qi, Qing;  Li, Heng   |  收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 Systemic sclerosis  SAHH inhibitor  Fibrosis  Inflammation  Vasculopathy  TGF-beta   Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL ANALYSIS, 2019, 卷号: 9, 期号: 1, 页码: 25-33 作者:  Jia, Weiwei;  Li, Jing;  Du, Feifei;  Sun, Yan;  Xu, Fang   |  收藏  |  浏览/下载：25/0  |  提交时间：2020/07/01 S-adenosyl-L-homocysteine hydrolase  DZ2002  Carboxylesterases  Pharmacokinetics   Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal -actinin-4 expression and stabilizing integrin-cytoskeleton linkage 期刊论文  OAI收割 ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 页码: 16 作者:  He, Shijun;  Liu, Xing;  Lin, Zemin;  Liu, Yuting;  Gu, Lei   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 SAHH inhibitor  Lupus nephritis  -Actinin-4  Integrin-linked kinase  Integrin  Focal adhesion   Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage 期刊论文  OAI收割 Arthritis Research & Therapy, 2019, 卷号: 21, 期号: 1 作者:  He,Shijun;  Liu,Xing;  Lin,Zemin;  Liu,Yuting;  Gu,Lei   |  收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 SAHH inhibitor  Lupus nephritis  α-Actinin-4  Integrin-linked kinase  Integrin  Focal adhesion   Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-alpha/IFN-gamma-induced inflammatory response in keratinocytes and T cell-derived IL-17 期刊论文  OAI收割 PHARMACOLOGICAL RESEARCH, 2018, 卷号: 129, 页码: 443-452 作者:  Lin, Ze-Min;  Ma, Meng;  Li, Heng;  Qi, Qing;  Liu, Yu-Ting   |  收藏  |  浏览/下载：51/0  |  提交时间：2019/01/08 Reversible S-adenosyl-L-homocysteine  hydrolase inhibitor  Keratinocyte  Inflammation  Interleukin-17  Imiquimod  Psoriasis   可逆型的S-腺苷同型半胱氨酸水解酶抑制剂DZ2002对银屑病的治疗作用及机制研究 期刊论文  OAI收割 中国药理学与毒理学杂志, 2016, 卷号: 30, 期号: 10, 页码: 1089 作者:  林泽民;  马萌;  何世君;  唐炜;  左建平   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 SAHH抑制剂  银屑病  炎性浸润