中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [151]
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Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 7069
作者:
Zhou, Lin-Lin
;
Zhang, Tao
;
Xue, Yun
;
Yue, Chuan
;
Pan, Yihui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14
作者:
Xu, Zhuo
;
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Zhu, Mengying
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Otilonium Bromide
Deubiquitinase
USP28
Selective inhibitor
Structure-based discovery of potent USP28 inhibitors derived from Vismodegib
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Zhou, Di
;
Xu, Zhuo
;
Huang, Yaodong
;
Wang, Hui
;
Zhu, Xiaoli
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
USP28
Structure-based
Vismodegib derivatives
Structure-activity relationships
c-Myc
Shape and Shear Stress Impact on the Toxicity of Mesoporous Silica Nanoparticles: In Vitro and In Vivo Evidence
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 6, 页码: 3187-3201
作者:
Cheng, Yaxin
;
Tao, Jinsong
;
Zhang, Yaqi
;
Xi, Long
;
Han, Run
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
mesoporous silica nanoparticles (MSNs)
toxicity
shape
shear stress
in vitro blood flow model
Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 650, 页码: 117-122
作者:
Ni, Yicheng
;
Luo, Zhongyuan
;
Lv, Yixin
;
Ma, Shuyuan
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Thioredoxin reductase 1 inhibitor
Chemical probe
High -throughput screening
Thimerosal
Novel HER2-Targeted Peptide for NIR-II Imaging of Tumor
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 2, 页码: 1394-1403
作者:
Cao, Rui
;
Li, Renda
;
Shi, Hui
;
Liu, Hongguang
;
Cheng, Zhen
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
NIR-II
peptide
HER2
tumor
optical imaging
Acid-Ionizable Iron Nanoadjuvant Augments STING Activation for Personalized Vaccination Immunotherapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2023, 页码: 15
作者:
Chen, Fangmin
;
Li, Tianliang
;
Zhang, Huijuan
;
Saeed, Madiha
;
Liu, Xiaoying
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
acid-ionizable nanoadjuvants
cancer vaccines
iron oxide nanoparticles
personalized immunotherapy
STING cascade activation
The genetic diversity, replication, and transmission of 2009 pandemic H1N1 viruses in China
期刊论文
OAI收割
FRONTIERS IN MICROBIOLOGY, 2023, 卷号: 14
作者:
Sun, Hailiang
;
Wang, Yongcui
;
Liu, Hanlin
;
Pang, Zifeng
;
Cui, Xinxin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/01
In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2022, 卷号: 208, 页码: 10
作者:
Shang, Weijuan
;
Dai, Wenhao
;
Yao, Cheng
;
Xu, Ling
;
Tao, Xiangming
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
SARS-CoV-2
SARS-CoV-2 variants
FB2001
Main protease
PBPK
Anti-SARS-CoV-2 in vivo
Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors
期刊论文
OAI收割
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:
Zhang,Pei
;
Du,Yang
;
Bai,Hua
;
Wang,Zhijie
;
Duan,Jianchun
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/11/21
Tucidinostat
Tumor microenvironment
PD-L1
CCL5
Solid tumor