中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [32]
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期刊论文 [126]
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Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants
Flavonoids from Hippophae rhamnoides Linn. Revert Doxorubicin-Induced Cardiotoxicity through Inhibition of Mitochondrial Dysfunction in H9c2 Cardiomyoblasts In Vitro
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 4
作者:
Zhou, Wenna
;
Ouyang, Jian
;
Hu, Na
;
Wang, Honglun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/01
Tribulus terrestris L. extract ameliorates atherosclerosis by inhibition of vascular smooth muscle cell proliferation in ApoE(-/-) mice and A7r5 cells via suppression of Akt/MEK/ERK signaling
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 297, 页码: 15
作者:
Zhang, Jing
;
Zhao, Wai-Rong
;
Shi, Wen-Ting
;
Tan, Jun-Jie
;
Zhang, Kai-Yu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Plaque progression
Hyperlipidemia
Mitogen-activated protein kinases
Oxidized low density lipoprotein
VSMC phenotype Switching
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
期刊论文
OAI收割
EMBO REPORTS, 2022
作者:
Li, Hui
;
Wang, Ning
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/12/22
IL-17R signaling
inflammation
MEKK2
NEDD4L
ubiquitination
Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
作者:
Li,Xu-xia
;
Zhang,Peng
;
Yang,Yang
;
Wang,Jing-jing
;
Zheng,Yan-jun
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/04/02
cardiac hypertrophy
pyrazine derivative
QF84139
phenylephrine
transverse aortic constriction
AMPK signaling pathway
PROTEIN-KINASE
MAMMALIAN TARGET
OVERLOAD
METFORMIN
MACROPHAGES
MECHANISMS
MEDICINE
ALPHA
CELLS
MODEL
Anti-inflammatory activity of Anchusa italica Retz. in LPS-stimulated RAW264.7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling pathways
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 286, 期号: 3, 页码: 1-9
作者:
Duan, XM (Duan, Xiaomei) [1] , [2]
;
Li, J (Li, Jun) [1] , [2]
;
Cui, JX (Cui, Jingxue) [1] , [2]
;
Dong, YW (Dong, Yuwei) [1] , [2]
;
Xin, XL (Xin, Xuelei) [1] , [2]
  |  
收藏
  |  
浏览/下载:158/0
  |  
提交时间:2022/05/17
Boraginaceae
Anchusa italica Retz.
Anti-inflammatory
Edible Bird's Nest, an Asian Health Food Supplement, Possesses Moisturizing Effect by Regulating Expression of Filaggrin in Skin Keratinocyte
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 18
作者:
Lai, Queenie Wing Sze
;
Guo, Maggie Sui Sui
;
Wu, Kevin Qiyun
;
Liao, Zhitao
;
Guan, Dongshi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/01/12
edible bird's nest
sialic acid
moisturizing
filaggrin
filaggrin-2
atomic force microscopy
海胆及深海细菌免疫调节活性多糖的发现、结构表征和机制研究
学位论文
OAI收割
生物楼5楼会议室: 中国科学院海洋研究所, 2021
作者:
王清池
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/06/07
多糖
海胆
细菌
结构表征
生物活性
Increasing the Sampling Efficiency of Protein Conformational Change by Combining a Modified Replica Exchange Molecular Dynamics and Normal Mode Analysis
期刊论文
OAI收割
JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2021, 卷号: 17, 期号: 1, 页码: 13-28
作者:
Peng, Cheng
;
Wang, Jinan
;
Shi, Yulong
;
Xu, Zhijian
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
Structure and immunomodulatory activity of a water-soluble alpha-glucan from Hirsutella sinensis mycelia
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 189
作者:
Rong, Lin
;
Li, Guoqiang
;
Zhang, Yuxia
;
Xiao, Yuancan
;
Qiao, Yajun
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2021/11/18
Hirsutella sinensis
alpha-Glucan
Structure
Immunomodulatory activity